ID   A1CBH1_ASPCL            Unreviewed;       723 AA.
AC   A1CBH1;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   24-JAN-2024, entry version 73.
DE   SubName: Full=XPG N-terminal domain protein {ECO:0000313|EMBL:EAW13089.1};
GN   ORFNames=ACLA_015270 {ECO:0000313|EMBL:EAW13089.1};
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW13089.1, ECO:0000313|Proteomes:UP000006701};
RN   [1] {ECO:0000313|EMBL:EAW13089.1, ECO:0000313|Proteomes:UP000006701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC   {ECO:0000313|Proteomes:UP000006701};
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- SIMILARITY: Belongs to the XPG/RAD2 endonuclease family.
CC       {ECO:0000256|ARBA:ARBA00024023}.
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DR   EMBL; DS027049; EAW13089.1; -; Genomic_DNA.
DR   RefSeq; XP_001274515.1; XM_001274514.1.
DR   AlphaFoldDB; A1CBH1; -.
DR   STRING; 344612.A1CBH1; -.
DR   EnsemblFungi; EAW13089; EAW13089; ACLA_015270.
DR   GeneID; 4706356; -.
DR   KEGG; act:ACLA_015270; -.
DR   VEuPathDB; FungiDB:ACLA_015270; -.
DR   eggNOG; ENOG502QVHA; Eukaryota.
DR   HOGENOM; CLU_378548_0_0_1; -.
DR   OMA; FYQTKVI; -.
DR   OrthoDB; 6876at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd09902; H3TH_MKT1; 1.
DR   CDD; cd09858; PIN_MKT1; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR022039; MKT1_C.
DR   InterPro; IPR037314; MKT1_H3TH.
DR   InterPro; IPR022040; MKT1_N.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR11081:SF32; POST-TRANSCRIPTIONAL REGULATOR MKT1; 1.
DR   Pfam; PF12246; MKT1_C; 1.
DR   Pfam; PF12247; MKT1_N; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00485; XPGN; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          1..99
FT                   /note="XPG N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00485"
SQ   SEQUENCE   723 AA;  81207 MW;  41FAC515CF57888D CRC64;
     MPIRPLGEWA AARTQSLPLS ALKGAVVGID ASHYISQHLL HHSTREPLLV ALGGFPFALK
     SNIEKELQIF KELGVGCLFV FNGLDFGKKD QRPQAQAESV RAFEQAWELY DQQQADQVVD
     AFSSAGTPRP GSLYKFLQRI LYQNGVDFIV APYSAAAQLS YLAQGSNPVI DTIFGPSEVL
     LFDVDKLITR IDIEPSQFLW ITKQSCQEEL GRLSSDQFLD FCLLLGSSFL RTIPAFENPA
     FPGKAVTVRD ALPVFNQAGR NALALCAQFE EDRRMQDIQY TDLYKRAFMT VKHHVIMDVD
     GKVAPMDSDN APSDMHELIG QRLPEELYFY LSRGVLGPEI PNNLTSGEVK ISLPLGVEDT
     EIYRQTASTT LTPIRTQSIC LLSNSLHRFY QTKMINVRTW FDEKSDTSIN LKTLPSVKET
     IQAWKIHSHQ LPDELKKLQS TTSPLKFAVQ SLKDGDVISK SFTASKDSQK PLSTQEEILA
     NVYWRFLQLR GYIDEKNQLT PWGVCLEQAL SVLDPSGNLE EATLLAIEMA RFGLLNSRQW
     FSHVSGGPMR GSDEDKKFNI LISRVACIAK LQHKNIGYSG PLSRQLLCYR SLISEVRSTL
     RDLIEVVLTG LLLSGDAVRD RNDWSELSLK LPFIDDNDCG LGIAVRTYLD DLPLQADPTS
     PEARAEVKSK GKEWFQHSDS FAGNLDKAFK LWDAVYKGTQ NAGRDFKDAQ QWKDANNWLA
     ERR
//