ID A1CI10_ASPCL Unreviewed; 558 AA.
AC A1CI10;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE SubName: Full=Conserved membrane protein, putative {ECO:0000313|EMBL:EAW10515.1};
GN ORFNames=ACLA_049870 {ECO:0000313|EMBL:EAW10515.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW10515.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW10515.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027054; EAW10515.1; -; Genomic_DNA.
DR RefSeq; XP_001271941.1; XM_001271940.1.
DR AlphaFoldDB; A1CI10; -.
DR STRING; 344612.A1CI10; -.
DR EnsemblFungi; EAW10515; EAW10515; ACLA_049870.
DR GeneID; 4703949; -.
DR KEGG; act:ACLA_049870; -.
DR VEuPathDB; FungiDB:ACLA_049870; -.
DR eggNOG; KOG1120; Eukaryota.
DR HOGENOM; CLU_035821_2_0_1; -.
DR OMA; MNTDNTG; -.
DR OrthoDB; 155597at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0044695; C:Dsc E3 ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR Gene3D; 2.60.300.12; HesB-like domain; 1.
DR InterPro; IPR045226; Dsc3.
DR InterPro; IPR025390; Dsc3_C.
DR InterPro; IPR019413; Dsc3_ub-like_dom.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR NCBIfam; TIGR00049; iron-sulfur cluster assembly accessory protein; 1.
DR PANTHER; PTHR28049:SF1; DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR28049; TRANSMEMBRANE PROTEIN YOR223W; 1.
DR Pfam; PF13373; Dsc3_C; 1.
DR Pfam; PF10302; Dsc3_N; 1.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR SUPFAM; SSF89360; HesB-like domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 508..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..234
FT /note="FeS cluster biogenesis"
FT /evidence="ECO:0000259|Pfam:PF01521"
FT DOMAIN 261..366
FT /note="DSC E3 ubiquitin ligase complex subunit 3 ubiquitin-
FT like"
FT /evidence="ECO:0000259|Pfam:PF10302"
FT DOMAIN 421..555
FT /note="DSC E3 ubiquitin ligase complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13373"
FT REGION 39..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 558 AA; 60629 MW; 4F4E4B236EC0917C CRC64;
MSLYKVAMHS PVTSSATMLR CASKPFNTRC AQAARSFSSL GSTYRSSKRD MQTATAYRPH
TLPASFPPLS RSAGTPDTSI AAEFPPMSNT TLNKQDRNGS FSNVSLREQE AQKSRPAATP
SLTGSKSAEK PRRKLRARKA AMKLTPIAVE QLHKLLSQPD PKFIRVGVKN RGCSGLAYHL
EYVDKPGAFD EVVEQDGVKV LIDSKALFSI IGSEMDWQED KLSRKFIFRN PNISIQATMT
SPSFLTPDSI LDRDTAAEPL FLTIRFSASI PDLPLDVLSP DVTTAAGLKQ LIRTRLPRDL
SSHRLRLIYA GRGLEDATPL SASLKLPPSP SRTPIPQEDV AAAKGKGKAP VREQPRLYVH
CSIGDIVLSD ADLAAEAAIA TTLQQEQGQE QEQPDDFSFS KKGKQHQRQP SPLRSTTSAP
RGFDRLLSAG FTPAEVSALR SQFMAIQSVS RTPDTMPTGA ELRELEDRWM DEGSTSMGAG
LGGGGEGASF ADDDGGFGAG SRGAMDDMLW GAVMGFFWPV GCAMWLRREE GVWSWRKGLA
VFVGVVVNVA FGAMRIMN
//
