ID A1CYH8_NEOFI Unreviewed; 657 AA.
AC A1CYH8;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=NAD+ kinase Utr1, putative {ECO:0000313|EMBL:EAW23798.1};
GN ORFNames=NFIA_033640 {ECO:0000313|EMBL:EAW23798.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW23798.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SIMILARITY: Belongs to the NAD kinase family.
CC {ECO:0000256|ARBA:ARBA00010995}.
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DR EMBL; DS027686; EAW23798.1; -; Genomic_DNA.
DR RefSeq; XP_001265695.1; XM_001265694.1.
DR AlphaFoldDB; A1CYH8; -.
DR STRING; 331117.A1CYH8; -.
DR EnsemblFungi; EAW23798; EAW23798; NFIA_033640.
DR GeneID; 4592267; -.
DR KEGG; nfi:NFIA_033640; -.
DR VEuPathDB; FungiDB:NFIA_033640; -.
DR eggNOG; KOG2178; Eukaryota.
DR HOGENOM; CLU_008831_7_2_1; -.
DR OMA; EHMLKYW; -.
DR OrthoDB; 455155at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR HAMAP; MF_00361; NAD_kinase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002504; NADK.
DR PANTHER; PTHR20275; NAD KINASE; 1.
DR PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR Pfam; PF01513; NAD_kinase; 1.
DR Pfam; PF20143; NAD_kinase_C; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EAW23798.1};
KW NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 171..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..624
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 71482 MW; F4D3C1255F53E464 CRC64;
MASSSSSHGP LRLQSDSLPS ESSALSSSSS PPLSSATPLS GPASPDSCPL TSTTVGASLL
RDYASHIDPS QSTNDLHVNQ PTSGLSNSRA NVLQKLELRQ EEAPPVASLP TSPFLSFRSA
GPLGSQHRKN ASSSDLIPRQ TIMKALASRP SLCTNPNSNA PLAASLGLLA TSPNSSSSAE
TEQQRSSNSS SQKLSAALSN LQLGKYLERS PSTAQLVLQS PCFFHRRFDD AVNIQKVLEE
ISDDEWLSHS RLVQTATGVR EVSKQLQRRP IKRAVKNVMI VTKARDNRLV HLTRELAEWL
LSTPRYGSDL GVNVWVDSKL RNSKRFDAAG LLQSEPRFEQ MLHYWTPDLC WAAPEKFDLV
LTLGGDGTVL FTSWLFQRIV PPVLCFSLGS LGFLTNFEFE NYKSHLNDVM GDVGMRVNLR
MRFTCTVFRK DRSKGAEAGA VEEGEQFEVL NELVIDRGPS PYVSNLELYA DNDLLTVVQA
DGCIFSTPTG STAYSLSAGG SLIHPSIPGI LLTPICPHTL SFRPMVLSDS LLLRIAVPTG
SRSSAYCSFD GKGRVELRQG DYVTVEASQY PFPTVVSGSG EWFESVQRAL RWNTRGAVQK
SWNRDGTDDI SADEEEEEWD IDTDAGLVGT DSGLGPSEDG ESGTTSPMKR QMSLLNM
//
