ID A1D1I9_NEOFI Unreviewed; 819 AA.
AC A1D1I9;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Anaphase-promoting complex subunit 4 {ECO:0000256|ARBA:ARBA00016067};
GN ORFNames=NFIA_009620 {ECO:0000313|EMBL:EAW22282.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22282.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027688; EAW22282.1; -; Genomic_DNA.
DR RefSeq; XP_001264179.1; XM_001264178.1.
DR AlphaFoldDB; A1D1I9; -.
DR STRING; 331117.A1D1I9; -.
DR EnsemblFungi; EAW22282; EAW22282; NFIA_009620.
DR GeneID; 4592220; -.
DR KEGG; nfi:NFIA_009620; -.
DR VEuPathDB; FungiDB:NFIA_009620; -.
DR eggNOG; KOG4640; Eukaryota.
DR HOGENOM; CLU_011501_0_0_1; -.
DR OMA; FEPMKEF; -.
DR OrthoDB; 2722114at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024789; APC4.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR024790; APC4_long_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13260; ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4; 1.
DR PANTHER; PTHR13260:SF0; ANAPHASE-PROMOTING COMPLEX SUBUNIT 4; 1.
DR Pfam; PF12896; ANAPC4; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 27..132
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT DOMAIN 285..485
FT /note="Anaphase-promoting complex subunit 4 long"
FT /evidence="ECO:0000259|Pfam:PF12896"
SQ SEQUENCE 819 AA; 90927 MW; 68DB7B99E10FE29C CRC64;
MAEEVFKPQL TPVGEKSLPA KCKASTLTYC PTMDLIALVT EDEELRVFRL NGQKVFGGSF
KGDPYLGEDE ADGEIRAVRW KDNGNLLAVA CADDTVRLIS AYSGKTVHHY PADQPGAHAQ
PVSITCLGWG VNFTDSKAAQ RHLQEAAGQL TVSDLLSPDT QPSKAAALLK ADLPRELALL
DIESSLPKLS TLPATGSDSR ASIDAIFHSS SKNSNDAVDV LLVGFDDGTV HLRIFDCFEI
GSFKIGISDG GSSACRILQH ASHPLSSTHA LLASASTPGS SGGLHLLTID LRFITRSGRY
LSLLAYKTTQ LQNLLRYIGQ VQRQIELEWK NAQELPARYM RSINEDLKDK CHCDFVTAAY
HLVVTGDCFE PLKEFLVDIV GERGHKRWEK AVSSGYENVR RLTHECLLPA LERCEVLLSR
LIGLSRFQKL SEVLGLETND LNASVETLDC LHLLCHQILI NANEELAQFI AFSQWLRHEI
DMQTAEPMSQ TLDELMEKTD MIDYPQTLKY IRGALTKSTL QHFIQQLPMM GVPVAKPSAT
SDKWTAADDR PFYDTFKKLL EQLNQGQNNA NPPELPKMND LTKRLGLQFE KVFRQIAITQ
RRGILHRSPL ALHPDADQEV IDITMCSENS EDGTVSVIYI AVRSIKSHHL LYIYRVVSDS
ENGVSSTRQI CIGALNLQEG EIRQIQFVQD DTMMLLWSND KGSAYLLNIP FQPASTFDNE
GAFSSPSPFF ITYSDKLLDS TSPQPTIDAT TLDLLSPHST HASLIKHAFS PSGQKARPLR
FDVNGRKGRR AICVLYGDGL RYEVLDMDAE MADEDEDSE
//
