ID A1DBM3_NEOFI Unreviewed; 365 AA.
AC A1DBM3;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=NAD-binding Rossmann fold oxidoreductase family protein {ECO:0000313|EMBL:EAW20263.1};
GN ORFNames=NFIA_098970 {ECO:0000313|EMBL:EAW20263.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW20263.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027694; EAW20263.1; -; Genomic_DNA.
DR RefSeq; XP_001262160.1; XM_001262159.1.
DR AlphaFoldDB; A1DBM3; -.
DR STRING; 331117.A1DBM3; -.
DR EnsemblFungi; EAW20263; EAW20263; NFIA_098970.
DR GeneID; 4588302; -.
DR KEGG; nfi:NFIA_098970; -.
DR VEuPathDB; FungiDB:NFIA_098970; -.
DR eggNOG; KOG2741; Eukaryota.
DR HOGENOM; CLU_023194_25_2_1; -.
DR OMA; GLEWSIY; -.
DR OrthoDB; 2735190at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43708; CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR43708:SF1; GALACTOSE_LACTOSE METABOLISM REGULATORY PROTEIN GAL80; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT DOMAIN 4..126
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 143..360
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 365 AA; 39652 MW; 49770214195B557C CRC64;
MAPIRVGIIG LSPGAWAANA HLPYLQMPDS KFEIVAICNS SVESAAKSVK DLGLAEGVKT
YGNVQDIAYD KDVDLVVCAT RVDRHYTSIL PSLKAGKNVF VEWPLGRNLE EAKELLIVAK
QNNVKLAAVG LQGRFEATVE TLKSVLAEGR IGKVLSTTIT GQGLIGGQTE LESQTYLLDR
NSGGSLLTIP CLHLIDTVCE ALGEFSSFQS LLSNQRPVVK IVKSDGSVVK ENTEKTNPDH
VMIQGTLISG AVFSASIRGG APFKGSPGLE WSIYGEKGEI RISGPNSFIE VSGTTSFELH
DFNTDKVEKI EFQKGTFAEL SPMHRNMARI YEAIAAGNKS ILCDFEEAVK RHEFIEEVYN
QNPMF
//
