ID A1DIY3_NEOFI Unreviewed; 791 AA.
AC A1DIY3;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Cellobiose dehydrogenase {ECO:0000313|EMBL:EAW19340.1};
GN ORFNames=NFIA_093020 {ECO:0000313|EMBL:EAW19340.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW19340.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; DS027696; EAW19340.1; -; Genomic_DNA.
DR RefSeq; XP_001261237.1; XM_001261236.1.
DR AlphaFoldDB; A1DIY3; -.
DR STRING; 331117.A1DIY3; -.
DR EnsemblFungi; EAW19340; EAW19340; NFIA_093020.
DR GeneID; 4587795; -.
DR KEGG; nfi:NFIA_093020; -.
DR VEuPathDB; FungiDB:NFIA_093020; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_011025_0_0_1; -.
DR OMA; IGYLQCA; -.
DR OrthoDB; 52047at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR CDD; cd09630; CDH_like_cytochrome; 1.
DR Gene3D; 2.60.40.1210; Cellobiose dehydrogenase, cytochrome domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR015920; Cellobiose_DH_cyt.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR47190:SF2; CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620); 1.
DR PANTHER; PTHR47190; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF16010; CDH-cyt; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF49344; CBD9-like; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..791
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002634541"
FT DOMAIN 31..220
FT /note="Cellobiose dehydrogenase cytochrome"
FT /evidence="ECO:0000259|Pfam:PF16010"
FT DOMAIN 254..555
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 648..782
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 791 AA; 84426 MW; C5ABA45E60D3BB52 CRC64;
MKLLNRLSAA FFAASIVLEP CWAQSSTPVV YTDPATGITF DTWTVPTSQT AGGLTFGVAL
PSTALTTDAT EFIGYLQCAS TDATKTGWCG ISLKGSMTSN LLLMAWPYKD EILTSFRFSS
GYTMPDVYAG NATLTQISSS VNATHYTLLF RCQGCLAWNH NGVTGSAPTS AKQLVLGWAQ
AVAAPGSPSC PAQITLQQHD AQGIWVAKLD ASAASASYEQ WAALANKTVP GDCSGGGGGT
DPVGVPVPPG TTFDYVVVGG GAGGIVVADR LSEAGHSVLL IEKGPPSSGR WGGTMKPDWL
VGTNLTRFDV PGLCNQIWHD SAGIACDDID QMAGCVLGGG TAVNAALWWK PYPLDWTYNF
PAGWQAEDMV SPTNRVFNRI PWTVHPSADG KIYMQQGYNV IAGGLQAAGW KELTLNDNPS
WKNHTYGHTP YMFSHGERGG PMATYLVSAS KRNNFKLWMN TTVKRVVRTA DGHVTGVEVE
PFLDGGYEGV VNVTAKTGRV VLSAGTFGSA RILMRSGIGP SDQLDIVKSS SDGPTMIDKS
AWINLPVGMN LVDHVNTDTV ATHPDIVFYD FYAAYDDPIK SDASSYLNNR IGILTQSAPN
IGPIFFDEIR GADGITRQIQ WTARMEGGHD TPDDHAVVMS QYLGRGSTSR GRMTITANLD
TVVSTLPYLR DQHDVDAVIQ GLVNMQNALK GVGLNWTYPA PNITAEEFVN TMEITASTRR
ANHWLGTCKM GTDDGRKGGT AVVDTNTKVY GTDNLFVVDG SIFPGMVTSN PSAYIVIAAE
RAADRILALA T
//
