ID A1IGZ3_9ECHI Unreviewed; 280 AA.
AC A1IGZ3;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Transcription factor Hox4 {ECO:0000313|EMBL:BAF43723.1};
GN Name=MrHox4 {ECO:0000313|EMBL:BAF43723.1};
OS Metacrinus rotundus.
OC Eukaryota; Metazoa; Echinodermata; Pelmatozoa; Crinoidea; Articulata;
OC Isocrinida; Isocrinidae; Metacrinus.
OX NCBI_TaxID=228699 {ECO:0000313|EMBL:BAF43723.1};
RN [1] {ECO:0000313|EMBL:BAF43723.1}
RP NUCLEOTIDE SEQUENCE.
RA Hara Y., Yamaguchi M., Nakano H., Nonaka M., Amemiya S.;
RT "Expression patterns of Hox genes in larvae of the sea lily Metacrinus
RT rotundus.";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Antp homeobox family.
CC {ECO:0000256|RuleBase:RU004442}.
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DR EMBL; AB244521; BAF43723.1; -; mRNA.
DR AlphaFoldDB; A1IGZ3; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017995; Homeobox_antennapedia.
DR InterPro; IPR001827; Homeobox_Antennapedia_CS.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR45771; HOMEOTIC PROTEIN DEFORMED; 1.
DR PANTHER; PTHR45771:SF6; HOMEOTIC PROTEIN SEX COMBS REDUCED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00025; ANTENNAPEDIA.
DR PRINTS; PR00024; HOMEOBOX.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00032; ANTENNAPEDIA; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 184..244
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 186..245
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 243..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 280 AA; 31631 MW; 0AC82D19EB289C0F CRC64;
MNQKCSKTSL VDEDILYSGS ILPFKADMNS FLSSTSHAID PKFPPIEEYS QSSYIPTGQM
YGSQYSPFSS QHSSQSCSYS PYTSMATPSY GQWYADCNYD QLNSSQSGFA FSGGSVGSAT
EWGHKSPFQP TVPSVSQSCV DTAASFFRTT SQKATKLVDS QPRLYPWMKR LHVNPGLMAG
LAGMEAKRSR TSYTRQQILE LEKEFHFNRY LTRRRRIEIA QALGLSERQI KIWFQNRRMK
WKKDNNLPNT KNTKSATGSN RTVNSSNQET SVIKNTEETK
//
