ID A1JRC8_YERE8 Unreviewed; 477 AA.
AC A1JRC8;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=RNA polymerase sigma-54 factor {ECO:0000256|ARBA:ARBA00019942, ECO:0000256|PIRNR:PIRNR000774};
GN Name=rpoN {ECO:0000313|EMBL:CAL13785.1};
GN Synonyms=glnF {ECO:0000313|EMBL:CAL13785.1}, ntrA
GN {ECO:0000313|EMBL:CAL13785.1};
GN OrderedLocusNames=YE3759 {ECO:0000313|EMBL:CAL13785.1};
OS Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS 8081).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=393305 {ECO:0000313|EMBL:CAL13785.1, ECO:0000313|Proteomes:UP000000642};
RN [1] {ECO:0000313|EMBL:CAL13785.1, ECO:0000313|Proteomes:UP000000642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 13174 / 8081 {ECO:0000313|Proteomes:UP000000642};
RX PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA Prentice M.B.;
RT "The complete genome sequence and comparative genome analysis of the high
RT pathogenicity Yersinia enterocolitica strain 8081.";
RL PLoS Genet. 2:2039-2051(2006).
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|PIRNR:PIRNR000774}.
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798, ECO:0000256|PIRNR:PIRNR000774}.
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DR EMBL; AM286415; CAL13785.1; -; Genomic_DNA.
DR RefSeq; WP_005174257.1; NC_008800.1.
DR RefSeq; YP_001007913.1; NC_008800.1.
DR AlphaFoldDB; A1JRC8; -.
DR KEGG; yen:YE3759; -.
DR PATRIC; fig|393305.7.peg.4002; -.
DR eggNOG; COG1508; Bacteria.
DR HOGENOM; CLU_020569_0_1_6; -.
DR OrthoDB; 9814402at2; -.
DR Proteomes; UP000000642; Chromosome.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000774};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000774}.
FT DOMAIN 116..303
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 317..475
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
SQ SEQUENCE 477 AA; 53661 MW; 212FBECD05CBC207 CRC64;
MKQGLQLKFS QQLAMTPQLQ QAIRLLQLST LELQQEIQLA LESNPLLEQT DLHEEIEAKE
TIDSESLDTR EALEQKDMPE ELPLDATWDE IYTAGTPSGM GNDYSDDELP VYQGETTQTL
QDYLMWQVDL TPFSETDAAI ATSIVDAVDE TGYLTVPLED ILESMGDENV ALDEVEAVLK
RIQHFDPIGV AARNLRECLL VQLSQYDKDT PYLAEARLVI SEYLDLLGNH DFRTMIRLSR
LKEDTLKEAI ALIQSLDPRP GQSINTGESE YVIPDVLVRK DKGHWTVELN ADSIPRLKIN
QQYAAMGSNT RNDSDGQFIR SNLQEAKWLI KSLESRNETL LKVARCIVEQ QVAFFENGPE
FMKPMVLADI AQAVDMHEST ISRVTTQKFL HSPRGIFELK YFFSSHVNTD SGGEASSTAI
RALVKKLVAA ENPAKPLSDS KLTTLLCEQG IMVARRTVAK YRESLSIPPS NQRKQLV
//
