ID A1RY40_THEPD Unreviewed; 387 AA.
AC A1RY40;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Geranylgeranyl reductase {ECO:0000313|EMBL:ABL78120.1};
GN OrderedLocusNames=Tpen_0718 {ECO:0000313|EMBL:ABL78120.1};
OS Thermofilum pendens (strain DSM 2475 / Hrk 5).
OC Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC Thermofilum.
OX NCBI_TaxID=368408 {ECO:0000313|EMBL:ABL78120.1, ECO:0000313|Proteomes:UP000000641};
RN [1] {ECO:0000313|Proteomes:UP000000641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2475 / Hrk 5 {ECO:0000313|Proteomes:UP000000641};
RX PubMed=18263724; DOI=10.1128/JB.01949-07;
RA Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E.,
RA Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M.,
RA Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B.,
RA Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N.;
RT "Genome sequence of Thermofilum pendens reveals an exceptional loss of
RT biosynthetic pathways without genome reduction.";
RL J. Bacteriol. 190:2957-2965(2008).
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DR EMBL; CP000505; ABL78120.1; -; Genomic_DNA.
DR RefSeq; WP_011752385.1; NC_008698.1.
DR AlphaFoldDB; A1RY40; -.
DR STRING; 368408.Tpen_0718; -.
DR EnsemblBacteria; ABL78120; ABL78120; Tpen_0718.
DR GeneID; 4601483; -.
DR KEGG; tpe:Tpen_0718; -.
DR eggNOG; arCOG00570; Archaea.
DR HOGENOM; CLU_024648_0_0_2; -.
DR OrthoDB; 6062at2157; -.
DR Proteomes; UP000000641; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR NCBIfam; TIGR02032; GG-red-SF; 1.
DR PANTHER; PTHR42685:SF18; DIGERANYLGERANYLGLYCEROPHOSPHOLIPID REDUCTASE; 1.
DR PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000641}.
FT DOMAIN 3..288
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 387 AA; 41986 MW; 1F42DF813F5BD0C6 CRC64;
MQYDAAVVGA GPAGLMFARV LASKGFRVAV LEKNETLAVK PCGEGISARV LQTAEINRSD
TQRFVSHAIK GAVVVAPNGR KVVIKEEGEL GYVIDKRNFL RVMGEYAASY GADIYMKEPV
KEVVFKNGHW TVRARTVELE ARLLVGADGY LSYTAKALGL EKPGERRVIP TVQYVMPNVE
LEDPDMTYFF LGNEVAPKGY VWIFPKDGRL ANVGIGVQGA SPKAYLDKFI KNNPSIFGKA
RILEFRGAAV TIGGMLSEIV SEHAMLVGEA AGQVIPLTGG GIHTSIAGGK IAAEVASKAL
AEGDLSKKRL EEYKKLYNEY WGKRIRDSLK GLHAIEKMSD EELNQLAEIL SPQDVVNLAN
GENVASVALK LLKHPIFSIK LAKALLS
//
