ID A1SIE6_NOCSJ Unreviewed; 225 AA.
AC A1SIE6;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN OrderedLocusNames=Noca_2072 {ECO:0000313|EMBL:ABL81581.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL81581.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL81581.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|ARBA:ARBA00008640, ECO:0000256|RuleBase:RU366058}.
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DR EMBL; CP000509; ABL81581.1; -; Genomic_DNA.
DR RefSeq; WP_011755527.1; NC_008699.1.
DR AlphaFoldDB; A1SIE6; -.
DR STRING; 196162.Noca_2072; -.
DR KEGG; nca:Noca_2072; -.
DR eggNOG; COG0398; Bacteria.
DR HOGENOM; CLU_038944_4_2_11; -.
DR OrthoDB; 5242213at2; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF59; TVP38_TMEM64 FAMILY INNER MEMBRANE PROTEIN YDJZ; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU366058};
KW Membrane {ECO:0000256|RuleBase:RU366058};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW Transmembrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 73..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 121..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 157..175
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT DOMAIN 61..177
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 225 AA; 23327 MW; 7E93CF3AECCB62F5 CRC64;
MSRGVWLRLG LLVSLIGLLA AATLLTDAPT MSQIHDWTDA AGWAGVFVFV LVYVVFALIP
VPKAVLTLAA GALYGVPLGA ALALVGATTG AGVAFGAARL LGRDAVTRLE GRRLAWLDDV
LARRGFLAVL GLRLVPLVPY TVLNYGAGVT GVRWRSYLLA TILGMSPGAT LYATLGAHSD
EPASWPFVLA GAGLAVLSVL TAGVAWWRPR RGTTSGAAVA PADRE
//
