ID A1T5E3_MYCVP Unreviewed; 538 AA.
AC A1T5E3;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABM12393.1};
GN OrderedLocusNames=Mvan_1563 {ECO:0000313|EMBL:ABM12393.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM12393.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM12393.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000511; ABM12393.1; -; Genomic_DNA.
DR RefSeq; WP_011778818.1; NZ_JACKSD010000167.1.
DR AlphaFoldDB; A1T5E3; -.
DR STRING; 350058.Mvan_1563; -.
DR KEGG; mva:Mvan_1563; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_7_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05917; FACL_like_2; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABM12393.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009159}.
FT DOMAIN 23..395
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 446..522
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 538 AA; 59582 MW; 7241F890F5967A17 CRC64;
MSQSYDAGPT DTAILEETIG ANFERIAATY PDHEALVDVT GGRRWTYAEL DREIDTVAKG
LMSLGTESGD RVGIWAPNCP EWTIVQYATA KIGAILVNIN PAYRTHELSY VLEQSGVSTL
ISATRFKTSD YVAMVDEVRP DVPALQRVLF IGTDDWDRLR SRADVIDDAL LRERSASLSH
HDPVNIQYTS GTTGFPKGAT LSHRNILNNG FFVTEQIRLG PGDRLCIPVP FYHCFGMVMG
NLGCTTHGAT MVIPAPGFDP GQTLKTIETE RCTAVYGVPT MFIAMQNHAD FAERDLSSLR
TGIMAGAVCP VEVMKRCVEE MNMSEISIAY GMTETSPVSC QTLIDDDLER RTSSIGRVHP
HVEIKIVDPD TGHVVERGTP GEFCTRGYSV MLGYWRDEEK TAQAVDADGW MHTGDLAVMR
PDGYCNIVGR IKDVVIRGGE NIYPREVEEF LYTHPDIEDA QVVGVPDARY GEEICAWIRM
RPGRRALDAA AVREFAAGKL AHYKIPRYVH VVDEFPMTVT GKIRKVEMRE VSAGLFAD
//
