ID A1TDT3_MYCVP Unreviewed; 489 AA.
AC A1TDT3;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=HNH nuclease domain-containing protein {ECO:0000259|SMART:SM00507};
GN OrderedLocusNames=Mvan_4558 {ECO:0000313|EMBL:ABM15333.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM15333.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM15333.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
CC {ECO:0000256|ARBA:ARBA00023450}.
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DR EMBL; CP000511; ABM15333.1; -; Genomic_DNA.
DR AlphaFoldDB; A1TDT3; -.
DR STRING; 350058.Mvan_4558; -.
DR KEGG; mva:Mvan_4558; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_057500_1_0_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR003870; DUF222.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF02720; DUF222; 1.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009159}.
FT DOMAIN 369..420
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
FT REGION 126..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..148
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 53805 MW; D158E8D7EA697F22 CRC64;
MRQSDRLEVC FEELAELAGQ RNAIDGRIAQ IAAEIDGAGL WAITGVKSME GLIAWKLGTS
FRNAETIVAV ARRLEQFPRC SRDLREGRLS LDQVGVIAER AGAGSDDHYA DLAAHSTVAQ
LRIAVKQEPR PEPEPDRDPG RDCDPEAESG AECGSESESG ADCDPESESE AKPRRDPVPR
ASITKTSDEQ YTYWRIALPH EEAATFDTAL RSHHEALVAQ WKRDHDITDH TDGHDITDRT
DGHDTDGHDD NVGDHTDTDG RDITNPGPYY DGDGGEGVGR APLPDTVAAF WALVKAGWDV
EVARRPHGQH TTVVMHVDVK ERIAALHLGP ALSAAERRYL SCDATCEVWF ERHGQVIGSG
RTTRAISRRL RRALEHRDRT CVVPGCGATR GLHAHHIRHW EDGGLTELDN LVLVCPHHHR
LHHRGVITIT GPAERLTVTD SVGRHLEPGS LARPPTQSPP AVAPYQGPPG ERAQWKWYTP
FQPPPPTTN
//
