ID A1UFG5_MYCSK Unreviewed; 306 AA.
AC A1UFG5;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Chalcone and stilbene synthases domain protein {ECO:0000313|EMBL:ABL91573.1};
GN OrderedLocusNames=Mkms_2375 {ECO:0000313|EMBL:ABL91573.1};
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=189918 {ECO:0000313|EMBL:ABL91573.1};
RN [1] {ECO:0000313|EMBL:ABL91573.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:ABL91573.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP000518; ABL91573.1; -; Genomic_DNA.
DR AlphaFoldDB; A1UFG5; -.
DR STRING; 189918.Mkms_2375; -.
DR KEGG; mkm:Mkms_2375; -.
DR HOGENOM; CLU_034992_0_1_11; -.
DR OrthoDB; 9786288at2; -.
DR UniPathway; UPA00094; -.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT DOMAIN 27..154
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 172..304
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
SQ SEQUENCE 306 AA; 32619 MW; C74540E744F08094 CRC64;
MEYRNLALPL ERYPRLSGFT EANAAYVEVA TELGEQAVRS ALHEAHIRPD QVDAIVAVSS
TGVAVPTIDA TICSRLGFRP DVKRIPLFGL GCVAGAAGMA RVHDYLRGYP DHVAVLLSVE
LCSLTLQRDD TSIPALIGLC LFGDGAAAVV ATGADRAPAR GRPAPRVLAT RSRLFPDTAE
VMGWNVSSSG FQLVMSRDVP AMAQNHLGDE VDRFLADHGL TTNDVSTWIC HPGGPKVLEA
IHGAVGMPAD ALRHSWESMR DNGNISSASV LDVLDRTVAQ RPTDGTLGLM LAMGPGFGFE
LLLLSW
//
