ID A1UK54_MYCSK Unreviewed; 523 AA.
AC A1UK54;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABL93212.1};
GN OrderedLocusNames=Mkms_4020 {ECO:0000313|EMBL:ABL93212.1};
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=189918 {ECO:0000313|EMBL:ABL93212.1};
RN [1] {ECO:0000313|EMBL:ABL93212.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:ABL93212.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000518; ABL93212.1; -; Genomic_DNA.
DR AlphaFoldDB; A1UK54; -.
DR STRING; 189918.Mkms_4020; -.
DR KEGG; mkm:Mkms_4020; -.
DR HOGENOM; CLU_000022_59_0_11; -.
DR OrthoDB; 9803968at2; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABL93212.1}.
FT DOMAIN 42..385
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 436..501
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 523 AA; 56544 MW; 81167698F34EB5EB CRC64;
MTDLRPLWDT EAFSGVYAGH PGRLYRRGPA TITDLIAGTR CWTDREFLVH GDRRISYAAF
RGALGRVGAH LADLGVRPRD RVMVFGYNSP EWIVALFALL LQGAVPVLGN RWWSPAEVAH
AAELLDLRHI LTDTALDTDR PASPLADLAY AFDAPAGPAS HADEDVDIDE VAIVLFTSGS
SGLPKAVELS RRSVIANQQN ILTRNGRLPH LLNADSPQAV SLASTPMFHI GGLSSLLTHF
LTGGRIVLAQ GRFDPGQVMA LVERERVQVW GAVPTMAVRV LEHPEFGSRD LSSLRSWPLG
GAPVSPELLE RIRTQLPTLR ERGLSNTWGM TEAGGFLTVA DSRDLRARPG TVGRPYPVVE
LRIDRPDDDG VGEVLARSPT VMLGYAGRAD DDTVDADGWL HTGDLGHLDD DGYLYIDGRS
KDVVIRGGEN IACPHVEAAL ASHPAVVEAA ALGLPHPDLG EELAAVVVYR SGALPPTDDE
LRRHLAGIVS SFAVPTRWLI RTEPLPTLAG EKIDKKTLAT AFD
//
