ID   A1Z2S2_ECOLX            Unreviewed;       133 AA.
AC   A1Z2S2;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   Name=phoQ {ECO:0000313|EMBL:ABM53635.1};
OS   Escherichia coli.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562 {ECO:0000313|EMBL:ABM53635.1};
RN   [1] {ECO:0000313|EMBL:ABM53635.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EC970520 {ECO:0000313|EMBL:ABM53635.1};
RA   Zhang Y., Laing C., Steele M., Ziebell K., Johnson R., Clark C.,
RA   Benson A.K., Taboada E., Gannon V.P.J.;
RT   "Genome evolution in three of the major Escherichia coli O157:H7 lineage-
RT   specific polymorphism assay genotypes.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; EF174158; ABM53635.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1Z2S2; -.
DR   DIP; DIP-46182N; -.
DR   IntAct; A1Z2S2; 1.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd16954; HATPase_PhoQ-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR   PANTHER; PTHR45436:SF4; SENSOR PROTEIN PHOQ; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          1..127
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   133 AA;  14804 MW;  FBAFEF33FCB4B97C CRC64;
     MYQRKGVNIS LDISPEISFV GEQNDFVEVM GNVLDNACKY CLEFVEISAR QTDEHLYIVV
     EDDGPGIPLS KREVIFDRGQ RVDTLRPGQG VGLAVAREIT KQYEGKIVAG ESMLGGARME
     VIFGRQHSTP KDE
//