ID   A2A1C3_9BACT            Unreviewed;       489 AA.
AC   A2A1C3;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Reductive dehalogenase {ECO:0000313|EMBL:BAF45416.1};
DE   Flags: Fragment;
GN   Name=rdhA {ECO:0000313|EMBL:BAF45416.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:BAF45416.1};
RN   [1] {ECO:0000313|EMBL:BAF45416.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=17916062; DOI=10.1042/BA20070171;
RA   Nishimura M., Ebisawa M., Sakihara S., Kobayashi A., Nakama T., Okochi M.,
RA   Yohda M.;
RT   "Detection and identification of Dehalococcoides species responsible for in
RT   situ dechlorination of trichloroethene to ethene enhanced by hydrogen-
RT   releasing compounds.";
RL   Biotechnol. Appl. Biochem. 51:1-7(2008).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB268358; BAF45416.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2A1C3; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR012832; RDH.
DR   InterPro; IPR028894; RDH_dom.
DR   NCBIfam; TIGR02486; RDH; 1.
DR   Pfam; PF13486; Dehalogenase; 1.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          337..369
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAF45416.1"
SQ   SEQUENCE   489 AA;  53626 MW;  152B95EC6E66564B CRC64;
     LGLTGVTLGS ASALSPQFRD LDELANSAKV VNKRGWWVKE RDYGNPTIEI DWNLMKRRDL
     RGFSNWDYAS LMMAFPGGPP AFKANTPKQA AAVTAKAKEI WPDYAGPTIR DKALSSSFWA
     SAYGHSGYCR SQNQHGMPTE IPAPRPSAIN TPAWEGTPEE NAAMLRAVFS LVGLGPVIGT
     TMLDEKSQNF IWEYSGVSWT GDESVPGNKH IVLDSGITES YVDATSFHIP TSQKYVIATH
     NISCDGFLRR SMAGAGFSST EEMSYVRVAY AKSIVEQFIR GLGYNVTYGH DLQSAVAWDM
     WSGVGEHCRM GQVIGSPEYG GLLRTHAVFY TDLPLPVTNP IDAGFVKFCE TCGICAETCP
     VGAIQERGID RSWDNNCGQS WADDKQAGGS KVMYNIPGYK GWRCNLFSCA FTPCASACKS
     NCPFNAIGDG SFVHSIVKST VATSPIFNSF FTSMEGVLHY GKQDKDPASW WNSPDEWFIY
     GTHPNLLRQ
//