ID A2A821_MOUSE Unreviewed; 233 AA.
AC A2A821;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=Antizyme inhibitor 2 {ECO:0000313|Ensembl:ENSMUSP00000122240.2};
DE Flags: Fragment;
GN Name=Azin2 {ECO:0000313|Ensembl:ENSMUSP00000122240.2,
GN ECO:0000313|MGI:MGI:2442093};
GN Synonyms=Adc {ECO:0000313|MGI:MGI:2442093};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122240.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122240.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122240.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000122240.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122240.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A2A821; -.
DR SMR; A2A821; -.
DR PeptideAtlas; A2A821; -.
DR ProteomicsDB; 351312; -.
DR Antibodypedia; 31397; 105 antibodies from 21 providers.
DR Ensembl; ENSMUST00000147731.2; ENSMUSP00000122240.2; ENSMUSG00000028789.17.
DR AGR; MGI:2442093; -.
DR MGI; MGI:2442093; Azin2.
DR VEuPathDB; HostDB:ENSMUSG00000028789; -.
DR GeneTree; ENSGT00950000182995; -.
DR HOGENOM; CLU_026444_2_1_1; -.
DR Proteomes; UP000000589; Chromosome 4.
DR Bgee; ENSMUSG00000028789; Expressed in seminiferous tubule of testis and 140 other cell types or tissues.
DR ExpressionAtlas; A2A821; baseline and differential.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR002433; Orn_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR11482:SF4; ANTIZYME INHIBITOR 2; 1.
DR PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR PRINTS; PR01182; ORNDCRBXLASE.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 7..200
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122240.2"
FT NON_TER 233
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122240.2"
SQ SEQUENCE 233 AA; 24949 MW; 7B5AF0C3743C479E CRC64;
EELTLGASQA TSAEMELVQH IGVPASKIIC ANPCKQVAQI KYAAKHGVRL LSFDNEVELA
KVVKSHPSAK MVLCIATQDS HSLNHLSLRF GASLKSCRHL LENAKKSHVE VVGVSFHIGS
GCPDPQAYAQ SIADARLVFQ MGEELGHTMN ILDLGGGFPG LEGAKVRFEE MASVINSALD
LYFPEGCGVD ILAELGRYYV TSAFTVAVSI VAKREVLDQA SREEQTGAAP KSI
//
