ID A2QB20_ASPNC Unreviewed; 353 AA.
AC A2QB20;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Contig An01c0430, genomic contig {ECO:0000313|EMBL:CAK37364.1};
GN ORFNames=An01g13580 {ECO:0000313|EMBL:CAK37364.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK37364.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK37364.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. MetX family.
CC {ECO:0000256|ARBA:ARBA00006886}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM269989; CAK37364.1; -; Genomic_DNA.
DR RefSeq; XP_001389759.1; XM_001389722.2.
DR AlphaFoldDB; A2QB20; -.
DR EnsemblFungi; CAK37364; CAK37364; An01g13580.
DR GeneID; 4977832; -.
DR KEGG; ang:An01g13580; -.
DR VEuPathDB; FungiDB:An01g13580; -.
DR HOGENOM; CLU_028760_2_0_1; -.
DR OrthoDB; 5489509at2759; -.
DR Proteomes; UP000006706; Chromosome 2R.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR008220; HAT_MetX-like.
DR PANTHER; PTHR32268:SF15; HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350); 1.
DR PANTHER; PTHR32268; HOMOSERINE O-ACETYLTRANSFERASE; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF000443; Homoser_Ac_trans; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 54..302
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT ACT_SITE 125
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT ACT_SITE 296
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
FT ACT_SITE 327
FT /evidence="ECO:0000256|PIRSR:PIRSR000443-1"
SQ SEQUENCE 353 AA; 39632 MW; 5A3B3BDEC84C0377 CRC64;
MSQEEYDTFK LGDWELQSGE KLVDAHLAYK TFGDPASPAI VYPSWFSGLL SDNYWLIGED
KTLNPKKYFI IVPALFGNGQ STSPSNYAHP GPFPKCSFYD NVRAQHQLVT QHLKITHVRA
VIGWSMGAAQ TYQWATQYPD FMDLAVPFCG SAKTSLHNKV FLEGVKSALL AAKHIPSAGS
GNGGLLQAEQ SLRTWSDTEK EVGLKAFGRG YAGWGFSQAF YREKLYETAL GFKDLEDFMQ
NFWESWALSK DPGNLLTMLQ TWQNGDVSKQ EPYNGNFEKA LGSIKAKTLV LPSKTDLYFP
PEDSEYEVAF MQRGIGTLKV FPSIWGHWAG GPGQSKDDVK WLDEQLAEFF DKY
//
