ID A2QBV9_ASPNC Unreviewed; 631 AA.
AC A2QBV9;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Contig An02c0010, genomic contig {ECO:0000313|EMBL:CAK96356.1};
GN ORFNames=An02g01390 {ECO:0000313|EMBL:CAK96356.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK96356.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK96356.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; AM269996; CAK96356.1; -; Genomic_DNA.
DR RefSeq; XP_001399279.1; XM_001399242.2.
DR AlphaFoldDB; A2QBV9; -.
DR EnsemblFungi; CAK96356; CAK96356; An02g01390.
DR GeneID; 4978624; -.
DR KEGG; ang:An02g01390; -.
DR VEuPathDB; FungiDB:An02g01390; -.
DR HOGENOM; CLU_014456_0_0_1; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000006706; Chromosome 4R.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 97..213
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 21..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 631 AA; 70073 MW; 92C21378678C5C72 CRC64;
MWNDEDNNPY GAFDNEAHLS ESLHSATLPP TLYDREYTPP SPSSRSSTDN PPDFLSQQQD
LSDEDEAPDY ATQQAGHGYL RKSVYDSRIE QLLYENPEMP ILITDAGKNH EGGGSFIVYT
IRTGDLEVRR RYSEFASLRQ TLVNLHPTLV IPPIPEKHTM ADYAAKPTKA KEDTAIIDLR
KRMLAVFLNR CRRMKEVRED GVWWRFLDPN VSWSEVLHSH PASSVPKNNL KAPPLDPANP
TPAHAWLPVP SSSAKLKSAG GAAPAPAPAP ETPGPDVLGR FPPESRKLSE KELDPYFINF
EASTRELELL LQGNIEKVNR RTLAHLSSLS ADLMELGARY NGFSLSEPSP TVAAAIERVG
QAADTSYIET EELSSQLSAS FAEPMRESAQ FASVVRSVLR YRVLKRVQEE MTRDELAKKK
TLLDSLERSE MEAKRIEQYL NRTSPPGGAT RTQRSLSASS AVSAPGGTEG EARPAGSEDG
ASVESEFPPT HGDSINSHPP PTAQRRPDFG GASPAHRKTS SGTFVANKIF GRISHAVHGF
VDVDPERTRR DQIGKTKESL VQLEQALGVS EKDVKDASAG VLQDLKRFQK DKEMDLRRYM
VAYARCHLDW ARKNLETWTE AKDEVDKIVV R
//
