ID A2SAZ1_BURM9 Unreviewed; 425 AA.
AC A2SAZ1;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 2.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=Multidrug efflux RND membrane fusion protein MexE {ECO:0000313|EMBL:ABN01670.2};
GN Name=mexE {ECO:0000313|EMBL:ABN01670.2};
GN OrderedLocusNames=BMA10229_A3170 {ECO:0000313|EMBL:ABN01670.2};
OS Burkholderia mallei (strain NCTC 10229).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=412022 {ECO:0000313|EMBL:ABN01670.2, ECO:0000313|Proteomes:UP000002283};
RN [1] {ECO:0000313|EMBL:ABN01670.2, ECO:0000313|Proteomes:UP000002283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 10229 {ECO:0000313|EMBL:ABN01670.2,
RC ECO:0000313|Proteomes:UP000002283};
RA DeShazer D., Woods D.E., Nierman W.C.;
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000546; ABN01670.2; -; Genomic_DNA.
DR AlphaFoldDB; A2SAZ1; -.
DR KEGG; bml:BMA10229_A3170; -.
DR HOGENOM; CLU_018816_2_0_4; -.
DR Proteomes; UP000002283; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF36; SLL0180 PROTEIN; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 86..132
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 396..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 118..152
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 425 AA; 45071 MW; 5B90B6B2285DE949 CRC64;
MPAAFIGTST RMSMPFVTRR KLVAFALLSL GAITLAAWLV KPSADARAAA AKQADAAIPV
TAAIVGTMNL PVYLTGVGAV TPQYDVTVRS QVDGQITHVR FHEGQQVRAG DVLVEIDRRA
LQATADQATA KLEQDKATLA NARLELARHQ RLAEMNAAPV QMLDTWKARV NELHAQIRGD
QAAVQNARVA VDYTTIRAPI SGRIGFRLVD QGNLVKANDT ALLTLVTTSP ITAIYSESQD
ALPAIQAALR RGEVEAVAMS TDGETTLSHG RLRTIENRVD PTSGVVRMKA VFENADGALW
PGQSVMIRTV VDVLRNATAV PEDAIQIGPD GSFVYVIGAG DKVAMRPVEV SHRVLGYAAV
KHGLQAGERV VVQGQYRLQD GARVAATMMP AHDAPDAAAA GARNARAPAA GREAPAVPAT
NARRS
//
