ID   A2VRE2_9BURK            Unreviewed;       340 AA.
AC   A2VRE2;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Deacetylase {ECO:0000313|EMBL:EAY62288.1};
GN   ORFNames=BCPG_00515 {ECO:0000313|EMBL:EAY62288.1};
OS   Burkholderia cenocepacia PC184.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=350702 {ECO:0000313|EMBL:EAY62288.1, ECO:0000313|Proteomes:UP000053735};
RN   [1] {ECO:0000313|EMBL:EAY62288.1, ECO:0000313|Proteomes:UP000053735}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC184 {ECO:0000313|EMBL:EAY62288.1,
RC   ECO:0000313|Proteomes:UP000053735};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L.,
RA   Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E., Brockman W., Young S., LaButti K., DeCaprio D., Crawford M.,
RA   Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., White J.,
RA   Larson L., Alvarado L., Kodira C., Zeng Q., Yandava C., Oleary S.,
RA   LiPuma J., Lory S.;
RT   "The Genome Sequence of Burkholderia cenocepacia (strain PC184).";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the histone deacetylase family.
CC       {ECO:0000256|ARBA:ARBA00005947}.
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DR   EMBL; CH482377; EAY62288.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2VRE2; -.
DR   HOGENOM; CLU_007727_8_3_4; -.
DR   Proteomes; UP000053735; Unassembled WGS sequence.
DR   CDD; cd10001; HDAC_classII_APAH; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF9; HISTONE DEACETYLASE 8; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   3: Inferred from homology;
FT   DOMAIN          28..333
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   340 AA;  36971 MW;  C463783414F58453 CRC64;
     MKTYFHPEQL LHHPRSYLSR GQMREPQEVP ERAARLVAAV RSLDFDVREP ADRGTAPLAA
     VHDMNYLRFL EDAHRDWKQM PDDWGDEVMS NVFVRDPNPL RGVLAKAARY LADGSCPVGA
     STWRAAYWSA QGALAAAADV NDGAREAYAL CRPPGHHARR DAAGGFCYLN NAAIAAQALL
     GRHRRVAVLD TDMHHGQGVQ EIFYGRDDVL YVSIHGDPTN FYPVVAGYEE ETGAGAGDGF
     NLNLPMPHGA PESAFFERLD DALRALARFQ PDALVLALGF DIYKDDPQSQ VAVTTDGFGR
     LGGAIGALGL PTVIVQEGGY HLASLEANAR AFFGGFAAGR
//