ID A2W2S7_9BURK Unreviewed; 514 AA.
AC A2W2S7;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:EAY66273.1};
GN ORFNames=BCPG_04655 {ECO:0000313|EMBL:EAY66273.1};
OS Burkholderia cenocepacia PC184.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=350702 {ECO:0000313|EMBL:EAY66273.1, ECO:0000313|Proteomes:UP000053735};
RN [1] {ECO:0000313|EMBL:EAY66273.1, ECO:0000313|Proteomes:UP000053735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC184 {ECO:0000313|EMBL:EAY66273.1,
RC ECO:0000313|Proteomes:UP000053735};
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L.,
RA Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA Mauceli E., Brockman W., Young S., LaButti K., DeCaprio D., Crawford M.,
RA Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., White J.,
RA Larson L., Alvarado L., Kodira C., Zeng Q., Yandava C., Oleary S.,
RA LiPuma J., Lory S.;
RT "The Genome Sequence of Burkholderia cenocepacia (strain PC184).";
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CH482378; EAY66273.1; -; Genomic_DNA.
DR AlphaFoldDB; A2W2S7; -.
DR HOGENOM; CLU_000445_107_26_4; -.
DR Proteomes; UP000053735; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43531:SF7; AEROTAXIS RECEPTOR; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:EAY66273.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transferase {ECO:0000313|EMBL:EAY66273.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 169..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..60
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 271..500
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 514 AA; 55028 MW; A43A5399D6815F71 CRC64;
MRNNQPVTQQ EFDFPDDVTL MSTTDADSVI TYANTTFAQV SGFSNEELVG QPHNVVRHPD
MPKEAFVDMW ATLRRGEPWT ALVKNRRKNG DHYWVRANAI PVMRNGAPQG YMSVRTKAPH
DETRAADALY RAFREGKAGR RRFHKGLVIR TGLLRIASLS QTMSVRARVH SALCVLAPAV
VGAGWACGLT GGGFAAFAGV TVGVAAVAGW WLDAQIVQPL KRLHEQALNV ATGESRRGVR
MNRVDEIGMT LRTINQLGLM FRWLVDDVSE QVHNVQRASN EIAQGNGDLS ARTEQAASSV
QQTAASMAEM TATVSSNAET ALQANQLSVS ASDAAERGGQ AVSEVVTTMS EITASSRKIA
DIIGVIDGIA FQTNILALNA AVEAARAGEQ GRGFAVVAGE VRALAQRSAN AAKEIKTLIG
ASVERVESGA RIVDGAGKTM EDIVTQVKRV SDLIAEISSS TAEQSTGVAQ VDQAVVHLDN
ITQQNAALVE QSTAASESLK QQATRLVDAV NVFR
//
