ID   A2W4E9_9BURK            Unreviewed;       402 AA.
AC   A2W4E9;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:EAY66845.1};
GN   ORFNames=BCPG_05246 {ECO:0000313|EMBL:EAY66845.1};
OS   Burkholderia cenocepacia PC184.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=350702 {ECO:0000313|EMBL:EAY66845.1, ECO:0000313|Proteomes:UP000053735};
RN   [1] {ECO:0000313|EMBL:EAY66845.1, ECO:0000313|Proteomes:UP000053735}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC184 {ECO:0000313|EMBL:EAY66845.1,
RC   ECO:0000313|Proteomes:UP000053735};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L.,
RA   Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E., Brockman W., Young S., LaButti K., DeCaprio D., Crawford M.,
RA   Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., White J.,
RA   Larson L., Alvarado L., Kodira C., Zeng Q., Yandava C., Oleary S.,
RA   LiPuma J., Lory S.;
RT   "The Genome Sequence of Burkholderia cenocepacia (strain PC184).";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CH482379; EAY66845.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2W4E9; -.
DR   HOGENOM; CLU_017266_3_1_4; -.
DR   Proteomes; UP000053735; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   CDD; cd01066; APP_MetAP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR014335; Ectoine_EutD.
DR   InterPro; IPR000994; Pept_M24.
DR   NCBIfam; TIGR02993; ectoine_eutD; 1.
DR   PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR   PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:EAY66845.1};
KW   Hydrolase {ECO:0000313|EMBL:EAY66845.1};
KW   Protease {ECO:0000313|EMBL:EAY66845.1}.
FT   DOMAIN          24..169
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          176..385
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
SQ   SEQUENCE   402 AA;  44284 MW;  87FAD4D80EA2CBF2 CRC64;
     MSAVIETQTA APRLAFARSE YAARIAKTRA AMERAGIDLL IVTDPTNMGW LTGYDGWSFY
     VHQCVLLALD GEPVWFGRNQ DANGAKRTAF MAHENIVGYP DHYVQSSARH PMDYLSTEVI
     AARGWNTLRI GVELDNYYFS AAAYASLQKH LPGARWVDAT ALVNWQRAVK SPREIEYMRV
     AARIVERMHA HIVETIEPGM KKSDLVAQIY ATGIGGADGF GGDYPAIVPL LPTGADAAAP
     HLTWDDSTFA RGAGTFFEIA GCYRRYHCPL SRTVYLGKPP AHFIEGERAV VEGIEAGLAA
     AKPGNVCEDI ANAFFAVLRR AGIDKDSRCG YPIGASYPPD WGERTMSLRP GDRTVLEPGM
     TFHFMPGLWL DDWGLEITES ILITETGAET FCNVPRKLFV KE
//