ID A3CXT3_METMJ Unreviewed; 270 AA.
AC A3CXT3;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=NADPH-dependent FMN reductase {ECO:0000313|EMBL:ABN58183.1};
GN OrderedLocusNames=Memar_2260 {ECO:0000313|EMBL:ABN58183.1};
OS Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=368407 {ECO:0000313|EMBL:ABN58183.1, ECO:0000313|Proteomes:UP000002146};
RN [1] {ECO:0000313|EMBL:ABN58183.1, ECO:0000313|Proteomes:UP000002146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35101 / DSM 1498 / JR1
RC {ECO:0000313|Proteomes:UP000002146};
RX PubMed=21304656; DOI=10.4056/sigs.32535;
RA Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT type strain JR1.";
RL Stand. Genomic Sci. 1:189-196(2009).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the SsuE family. Isf subfamily.
CC {ECO:0000256|ARBA:ARBA00038292}.
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DR EMBL; CP000562; ABN58183.1; -; Genomic_DNA.
DR RefSeq; WP_011845092.1; NC_009051.1.
DR AlphaFoldDB; A3CXT3; -.
DR STRING; 368407.Memar_2260; -.
DR GeneID; 76730344; -.
DR KEGG; mem:Memar_2260; -.
DR eggNOG; arCOG02575; Archaea.
DR HOGENOM; CLU_050993_1_0_2; -.
DR OrthoDB; 9059at2157; -.
DR Proteomes; UP000002146; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.360; -; 1.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR005025; FMN_Rdtase-like.
DR PANTHER; PTHR43278:SF1; IRON-SULFUR FLAVOPROTEIN MJ1083; 1.
DR PANTHER; PTHR43278; NAD(P)H-DEPENDENT FMN-CONTAINING OXIDOREDUCTASE YWQN-RELATED; 1.
DR Pfam; PF03358; FMN_red; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 6..153
FT /note="NADPH-dependent FMN reductase-like"
FT /evidence="ECO:0000259|Pfam:PF03358"
SQ SEQUENCE 270 AA; 31123 MW; 0FC2FF63A1718517 CRC64;
MEDRPIKVLV IMGSARKANT YRAAERIREI LEEEAPVDWE YVMLKDVNLE QCRGCYTCFD
RGEEYCPIKD DSALLEEKMH AADGVIFATP VYGFQVSGLM KVFIDRHSYI FHRPRFFRQK
ALLLTTVGVM GDKDVLDYLN AVARIWGFEV AGRAGIVSHA KMGPLPAYRL RENEEKLQAA
AKAFLAALRR ETPRRPGLFN VMAFHIGRAP CDELGESAPA DHAYWKEQGW FERGRRYYVD
VPVNPVYHAL GMAAEWYMRR RVRRDLREVG
//
