ID A3DPK0_STAMF Unreviewed; 1060 AA.
AC A3DPK0;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Type II secretion system protein E {ECO:0000313|EMBL:ABN70560.1};
GN OrderedLocusNames=Smar_1471 {ECO:0000313|EMBL:ABN70560.1};
OS Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Staphylothermus.
OX NCBI_TaxID=399550 {ECO:0000313|EMBL:ABN70560.1, ECO:0000313|Proteomes:UP000000254};
RN [1] {ECO:0000313|Proteomes:UP000000254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43588 / DSM 3639 / JCM 9404 / F1
RC {ECO:0000313|Proteomes:UP000000254};
RX PubMed=19341479; DOI=10.1186/1471-2164-10-145;
RA Anderson I.J., Dharmarajan L., Rodriguez J., Hooper S., Porat I.,
RA Ulrich L.E., Elkins J.G., Mavromatis K., Sun H., Land M., Lapidus A.,
RA Lucas S., Barry K., Huber H., Zhulin I.B., Whitman W.B., Mukhopadhyay B.,
RA Woese C., Bristow J., Kyrpides N.;
RT "The complete genome sequence of Staphylothermus marinus reveals
RT differences in sulfur metabolism among heterotrophic Crenarchaeota.";
RL BMC Genomics 10:145-145(2009).
RN [2] {ECO:0000313|EMBL:ABN70560.1, ECO:0000313|Proteomes:UP000000254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43588 / DSM 3639 / JCM 9404 / F1
RC {ECO:0000313|Proteomes:UP000000254};
RX PubMed=21304655; DOI=10.4056/sigs.30527;
RA Anderson I.J., Sun H., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Tice H., Dalin E., Lucas S., Barry K., Land M., Richardson P., Huber H.,
RA Kyrpides N.C.;
RT "Complete genome sequence of Staphylothermus marinus Stetter and Fiala 1986
RT type strain F1.";
RL Stand. Genomic Sci. 1:183-188(2009).
CC -!- SIMILARITY: Belongs to the GSP E family.
CC {ECO:0000256|ARBA:ARBA00006611}.
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DR EMBL; CP000575; ABN70560.1; -; Genomic_DNA.
DR AlphaFoldDB; A3DPK0; -.
DR STRING; 399550.Smar_1471; -.
DR MEROPS; N10.007; -.
DR KEGG; smr:Smar_1471; -.
DR eggNOG; arCOG01817; Archaea.
DR eggNOG; arCOG03145; Archaea.
DR HOGENOM; CLU_289291_0_0_2; -.
DR Proteomes; UP000000254; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR CDD; cd01130; VirB11-like_ATPase; 1.
DR Gene3D; 3.30.450.380; -; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 2.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001482; T2SS/T4SS_dom.
DR NCBIfam; TIGR01443; intein_Cterm; 1.
DR NCBIfam; TIGR01445; intein_Nterm; 1.
DR PANTHER; PTHR30486:SF6; CONJUGAL TRANSFER PROTEIN RV3659C-RELATED; 1.
DR PANTHER; PTHR30486; TWITCHING MOTILITY PROTEIN PILT; 1.
DR Pfam; PF14890; Intein_splicing; 1.
DR Pfam; PF00437; T2SSE; 1.
DR PRINTS; PR00379; INTEIN.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 3: Inferred from homology;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000};
KW Reference proteome {ECO:0000313|Proteomes:UP000000254}.
FT DOMAIN 579..713
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 834..858
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 1060 AA; 122753 MW; BBA6AA28A10ED029 CRC64;
MFSRRERKER LTKLPGEEEV SEAVKSIIVP AEPIQVAKRD PSWRIIESYY VYKPFVKIVI
AETPQGPMYF VEEYGLTPSD KEVLEKLTDI LMDEIRPPTR PEDIKDLKGY VFKETERIAD
KYREKLGLVG ARKIKLLYYI ERNLLGYGPI DPLMKDPNIE DISCNGVNIP IYVWHKKYES
IPTNITFIDE DYLNEFVMKM AHMAGKHISI AFPILDAMLP EKHRLAATFG REVSVKGPTF
TIRKFRERPF SVTEIIQSGV INSLVAAYLW TLIEHGKTAM IAGGTGVGKT TMLNVISMFI
RPGMKIVTIE DTPEINLPHP NWVQLTSRET YLVGTSSLGT NIRLFDLVKL SLRYRPDYII
VGEVRGEEAF VLFQAMASVS YDTPVLIRDP INKIHLVKIG EFIDKFYEEG EERTAKHVNG
YYVLSHDGFQ VVWKPIKYVL RHRTNEIYEI IYEGGGKLEA TGSHSVFVLD PDTLDIVEKP
VMLLNKGEYL VSFNGVKENK DHQTIDLIDL VSDYNDVYVD NIPSELKKHT GGRNPIPLKQ
YMILRKRVIT KKNNSLIKLR RSKYTLPIRL VLDEKLAFLF GAYIANGCVK ERRDKLICFT
FGKSAKNIAD KVMNIMYEKF NIKPFIDDRG TYIIYEYPHT LLAIIFEKLL GRKLEEKKMP
EILWSSPKSV IRAFFEGLRA YSQRTLRRRY TSYTTANKNL AYQLLWLARF AGFYSVLKEE
KEAGKNNGKT YYHVIVYLDQ SYRKPNASER VPVKPILKLI KYTKPRTMPP ELAYIKRREF
ISRKTALKAL EWIRRDGSFT DFSREYLRKI ESLINGDIIV LKIKDVRKKQ YKGYVYDISV
PITEAFFGGN IPILLHNTGH GGLSTIHAET LDYAIKRLTS PPMNIPPTYM KLMNTFIHLQ
RVIARIEKGV VRVRRRATIV QEVEDFGKYR TIAVWDPRTD QFKVNLEESL HLRDIAAKRG
LELEDIIDEI YRKATVLNWM IYKNIFNVWD VSRIIFNYYY DPVSVYKRAV RELEEAGREA
GVPTMVAPEE VASTEELVGG TKEMGEATKE LFERTRELEK
//
