ID A3GF74_PICST Unreviewed; 623 AA.
AC A3GF74;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=D-xylulokinase {ECO:0000313|EMBL:EAZ63302.2};
DE EC=2.7.1.17 {ECO:0000313|EMBL:EAZ63302.2};
GN Name=XKS1 {ECO:0000313|EMBL:EAZ63302.2};
GN ORFNames=PICST_68734 {ECO:0000313|EMBL:EAZ63302.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:EAZ63302.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:EAZ63302.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ63302.2}.
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DR EMBL; AAVQ01000001; EAZ63302.2; -; Genomic_DNA.
DR RefSeq; XP_001387325.2; XM_001387288.1.
DR AlphaFoldDB; A3GF74; -.
DR STRING; 322104.A3GF74; -.
DR GeneID; 4850923; -.
DR KEGG; pic:PICST_68734; -.
DR eggNOG; KOG2531; Eukaryota.
DR HOGENOM; CLU_016149_5_0_1; -.
DR InParanoid; A3GF74; -.
DR OMA; PISCMYK; -.
DR OrthoDB; 1704034at2759; -.
DR Proteomes; UP000002258; Chromosome 1.
DR GO; GO:0004856; F:xylulokinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR PANTHER; PTHR10196:SF57; XYLULOSE KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:EAZ63302.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transferase {ECO:0000313|EMBL:EAZ63302.2}.
FT DOMAIN 138..272
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 321..569
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT REGION 466..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 69458 MW; 8841B19F02673F4B CRC64;
MTTTPFDAPD KLFLGFDLST QQLKIIVTDE NLAALKTYNV EFDSINSSVQ KGVIAINDEI
SKGAIISPVY MWLDALDHVF EDMKKDGFPF NKVVGISGSC QQHGSVYWSR TAEKVLSELD
AESSLSSQMR SAFTFKHAPN WQDHSTGKEL EEFERVIGAD ALADISGSRA HYRFTGLQIR
KLSTRFKPEK YNRTARISLV SSFVASVLLG RITSIEEADA CGMNLYDIEK REFNEELLAI
AAGVHPELDG VEQDGEIYRA GINELKRKLG PVKPITYESE GDIASYFVTR YGFNPDCKIY
SFTGDNLATI ISLPLAPNDA LISLGTSTTV LIITKNYAPS SQYHLFKHPT MPDHYMGMIC
YCNGSLAREK VRDEVNEKFN VEDKKSWDKF NEILDKSTDF NNKLGIYFPL GEIVPNAAAQ
IKRSVLNSKN EIVDVELGDK NWQPEDDVSS IVESQTLSCR LRTGPMLSKS GDSSASSSAS
PQPEGDGTDL HKVYQDLVKK FGDLYTDGKK QTFESLTARP NRCYYVGGAS NNGSIIRKMG
SILAPVNGNY KVDIPNACAL GGAYKASWSY ECEAKKEWIG YDQYINRLFE VSDEMNSFEV
KDKWLEYANG VGMLAKMESE LKH
//
