ID A3GGJ3_PICST Unreviewed; 1562 AA.
AC A3GGJ3;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 2.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAZ63943.2};
GN ORFNames=PICST_66478 {ECO:0000313|EMBL:EAZ63943.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:EAZ63943.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:EAZ63943.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ63943.2}.
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DR EMBL; AAVQ01000001; EAZ63943.2; -; Genomic_DNA.
DR RefSeq; XP_001387966.2; XM_001387929.1.
DR STRING; 322104.A3GGJ3; -.
DR GeneID; 4851392; -.
DR KEGG; pic:PICST_66478; -.
DR eggNOG; KOG4269; Eukaryota.
DR HOGENOM; CLU_245875_0_0_1; -.
DR InParanoid; A3GGJ3; -.
DR OMA; KQRSGYN; -.
DR OrthoDB; 25690at2759; -.
DR Proteomes; UP000002258; Chromosome 1.
DR GO; GO:0005933; C:cellular bud; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258}.
FT DOMAIN 1111..1220
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1359..1562
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 927..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1257..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 217..244
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..812
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1257..1276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1277..1291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1562 AA; 175135 MW; F61A876CEDEEE879 CRC64;
MDVSTRPEVA APYSPNNGSV TSAMKSNMTG HISSNNTNGI SNNNISNNDN IASSTNASKT
SNVNGSVASS FHDNNVANID STSTNNSTKL NSSQRFNQSY GGSPSSSSSN SSSSTNKPNV
TPNSSNHSNN VDNVINNNLS NLAYSYQPKS PISNSQLINS NTASPNGSSI YSPVTNRDSY
TLNMTIGSPR RGSNKLNDVP PSDPRFDRSH LTDKEFIEQL MFENRELHAL LSKKENQIQI
LREQWTVPKG IPVTITSSSV AELSTDSLES PIEKEEKTEE REAVKTEKQE REIQRQKDRQ
QREIEKEIER EIERDRVIQK EKERLQEREK ERQLLREREQ RNAPQSPGRR VSISNSPLPP
LPIDAEQQRE AQSPQSPRDT RGLGERRKEL KDQNKDAREK SIQETDDSED NQRDIYKETQ
REIQSNLLRE IQKREAQREN QRDAHREALR ESREREREQR ERQAQKERES QTEQISPRDA
RNEFPTDYHT EIPKESFNET PRIQREKESL QSLPSPDITN DSPVKSPVKL RQLAPATPQD
PSSSTFGIPP TPQQDFPPNI ITPEIPMRSS RRRRNSTDPP PSTLNSNANN SSQSPQPQAA
TAVSVLAQTA QQVVMKKASI VSIGSTSSSI PSAMSNVSAS TSVGKLANID KSLPDIEPSK
SAATNSDKLS NDLSTATTSS SSLIQPLPPL PTSPIRHNTF SPPTIVLPDS DSSPEKEQLD
NYSIVSPVDS KNFSPDLGQN RNFQSAPEKK MYSQARGSQS SGSFNQTNQY NQYKSRIKLP
PTLQQSGDSS VPPLPPAPPS LPPMPALPAP PTPTDGASNF GLRSPANLDT GNNDSVVTPN
VFGSQSRFNT PPSQATTQFS NTDYSATRRV PNTPDMLANG KFNMKLNEIP NPQLEEDSRS
YISSPMHGSF THSQVSPAQL STFDNNNEGM RTPANPDFSS GETTLKHSNQ TNQTPNSSFH
VMSSKKADED DTALFIRPED FQTINIYVVS TINVNSLNQA SKRSDDPNCT ISIHDRETNK
EMWRIRKTYS QLIAFDGEIR PIIEFFGLPA IPDKSLFLSN TPIKIEHRRA ALQNYFNTIF
MMPHIPHVVL YRMCRYLSLD FVNPLDDYKS GARKEGFLVR RHKGLGSNWK IRWCQVEGAY
MEIYENPGGP LIEQIKLKGA QVGRQSNDNV AEDKGYRHAF LIIESQKSSK LSSSLPKYFF
CAETDEERDS WVSTLVEFND LSDITMTSDM SDSMLATPAS NYQDELEYST KRYVSGNSIT
PGSAHVSNYD QGSSYTSHSQ EDKDSKESKK NKMRSIFPFR KNNSSHNQLS TDSILDEVDS
IPPPPYPANN QSTQHYLNQM NLDDNVAKKI FGREIEDAYK LSNTETLGRV VPSIVARCLD
YLIKTGSMYE EGIFRLSGSA STIRQLKEQF NTQFDLDLFE SPLKPDIHTV AGLLKTYLRE
LPSPILGLHP YNHLNSVILH NSTLPPVSLA LIFKEFINDR NNVDKIHYDM CYVIFKFLSQ
IIAQNQINRM NLRNVCIVFV PTLNISLEVL STCLVDFEYI FENGKPTPDK DREVLDLHIP
NF
//
