ID A3HRZ6_9BACT Unreviewed; 563 AA.
AC A3HRZ6;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN ORFNames=ALPR1_10375 {ECO:0000313|EMBL:EAZ82614.1};
OS Algoriphagus machipongonensis.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Algoriphagus.
OX NCBI_TaxID=388413 {ECO:0000313|EMBL:EAZ82614.1, ECO:0000313|Proteomes:UP000003919};
RN [1] {ECO:0000313|EMBL:EAZ82614.1, ECO:0000313|Proteomes:UP000003919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR1 {ECO:0000313|EMBL:EAZ82614.1,
RC ECO:0000313|Proteomes:UP000003919};
RX PubMed=21183675; DOI=10.1128/JB.01421-10;
RA Alegado R.A., Ferriera S., Nusbaum C., Young S.K., Zeng Q., Imamovic A.,
RA Fairclough S.R., King N.;
RT "Complete genome sequence of Algoriphagus sp. PR1, bacterial prey of a
RT colony-forming choanoflagellate.";
RL J. Bacteriol. 193:1485-1486(2011).
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ82614.1}.
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DR EMBL; AAXU02000001; EAZ82614.1; -; Genomic_DNA.
DR RefSeq; WP_008200336.1; NZ_CM001023.1.
DR AlphaFoldDB; A3HRZ6; -.
DR STRING; 388413.ALPR1_10375; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_9_10; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000003919; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EAZ82614.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003919}.
FT DOMAIN 30..420
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 470..544
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 563 AA; 62382 MW; 8C1C6B06C2FC35BD CRC64;
MQDFPWFKFY PKSVDKVVNC DAYGSVSELF EESVKKYGDS TAYECMGKTL SFNELDKLSS
HFANYLIHVL KLEQGSRVAL QMPNTLQYPV AMFGALRAGM IVVNTNPLYT SAEMKHQFND
AGADVIVIVA NFAHNLEKIR EEISAKRIII TELGDLLGFL KGTIVNLVVK HVKKMVPSYS
LPGADTFKSA LEQGAEYEFH APKIKKSDTA FLQYTGGTTG VSKGAELSHG NIIANMQQIS
EWMKPSLKER EEVVITALPL YHIFALTVNC LSMLKIGAHN VLITNPRDMP AFCKDLSKHK
FSVFTGVNTL FNGLLNQESF KNLDFSHLKI AVGGGMAVQK STAEKWKKVT GTPLAEGYGL
TETSPVASCN PIDGTERNGT IGIPLPNTEM CVMDDEGNML DIGERGEICI KGPQVMIGYW
NRPKETAEVM RGEWFKSGDI GIMDEDGFFK IVDRKKEMIL VSGFNVYPNE IEDVIASCEG
VLEVGVIGMP DPKSTEKVVA YVVPKGDSLS EDKVIAHCHE SLTNYKIPKE VYFTDELPKS
NVGKILRRKI KEAHMEKIGA KTK
//
