ID   A3I043_9BACT            Unreviewed;       658 AA.
AC   A3I043;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   SubName: Full=Putative aminopeptidase {ECO:0000313|EMBL:EAZ79839.1};
GN   ORFNames=ALPR1_14459 {ECO:0000313|EMBL:EAZ79839.1};
OS   Algoriphagus machipongonensis.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Algoriphagus.
OX   NCBI_TaxID=388413 {ECO:0000313|EMBL:EAZ79839.1, ECO:0000313|Proteomes:UP000003919};
RN   [1] {ECO:0000313|EMBL:EAZ79839.1, ECO:0000313|Proteomes:UP000003919}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PR1 {ECO:0000313|EMBL:EAZ79839.1,
RC   ECO:0000313|Proteomes:UP000003919};
RX   PubMed=21183675; DOI=10.1128/JB.01421-10;
RA   Alegado R.A., Ferriera S., Nusbaum C., Young S.K., Zeng Q., Imamovic A.,
RA   Fairclough S.R., King N.;
RT   "Complete genome sequence of Algoriphagus sp. PR1, bacterial prey of a
RT   colony-forming choanoflagellate.";
RL   J. Bacteriol. 193:1485-1486(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAZ79839.1}.
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DR   EMBL; AAXU02000001; EAZ79839.1; -; Genomic_DNA.
DR   RefSeq; WP_008201546.1; NZ_CM001023.1.
DR   AlphaFoldDB; A3I043; -.
DR   STRING; 388413.ALPR1_14459; -.
DR   eggNOG; COG0308; Bacteria.
DR   HOGENOM; CLU_015077_0_0_10; -.
DR   OrthoDB; 9814383at2; -.
DR   Proteomes; UP000003919; Chromosome.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:EAZ79839.1};
KW   Hydrolase {ECO:0000313|EMBL:EAZ79839.1};
KW   Protease {ECO:0000313|EMBL:EAZ79839.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003919};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..658
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002653265"
FT   DOMAIN          406..545
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   658 AA;  74765 MW;  4E7B7B64769BD6FE CRC64;
     MRKTLLFLLL STSFCFAQKE ELKPLRTSIE TDTRAIRQDV PMTNSIRKAF AEGTRDFTGK
     PGPNYWQMET DFTINASLDP STQTITGSEK IMVHNNSKDD LEAIVLRLDH NIFRADVPRG
     SSVPAEQTEG MIVTRITVGG EEVDLKAAPR RRNDPPALRA YGLTQTVATI SLVDPIKAGT
     SVELEIDWHT KLPGGDGGRG HRMTQRFDST LFQPTQWFPR LAKYDDLRGW ETSVYLGPAE
     FFNNFGKFDV SITMPEGWIV TGTGVLQNPE ELLTDKALDQ YSKVLESDEE LTIVGENDPK
     TQSGGEKTWH FVADKVNDFA WATSNKFIWK GTRANIPGKG YVPIYMVFIP ERARYFEQAA
     EKTRHAMEFY SELWAPYPFP QLTLQDGPSA GMEYPMVINS NQGAADHETA HQWWPMMLGT
     NETRYGWMDE GFNQYMNILS GADSRNEAYD LDGLGQRYGR ISGSEDEAPM MWSANNGGEG
     YGFQTYGKTP LMLSMLGGIV GDEAVIEGIR KYTDVWKYKH PSPWDFMFFM NHELDQNLEW
     FWYYWLFTTE AVDGSIENVE TVDGKTTVTV RQDGQMPAPV VLRVEFEDEG TDIKSLPNSK
     IIDENTVEVT WPVTVWFDGN KTFEAQMDFG GRKIKNITLD PHGRFPDYEV KDNVWPRK
//