ID A3IUJ9_9CHRO Unreviewed; 388 AA.
AC A3IUJ9;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Zinc-containing alcohol dehydrogenase superfamily protein {ECO:0000313|EMBL:EAZ89886.1};
GN ORFNames=CY0110_06359 {ECO:0000313|EMBL:EAZ89886.1};
OS Crocosphaera chwakensis CCY0110.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera; Crocosphaera chwakensis.
OX NCBI_TaxID=391612 {ECO:0000313|EMBL:EAZ89886.1, ECO:0000313|Proteomes:UP000003781};
RN [1] {ECO:0000313|EMBL:EAZ89886.1, ECO:0000313|Proteomes:UP000003781}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCY0110 {ECO:0000313|EMBL:EAZ89886.1,
RC ECO:0000313|Proteomes:UP000003781};
RA Stal L., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ89886.1}.
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DR EMBL; AAXW01000035; EAZ89886.1; -; Genomic_DNA.
DR RefSeq; WP_008277055.1; NZ_AAXW01000035.1.
DR AlphaFoldDB; A3IUJ9; -.
DR eggNOG; COG1063; Bacteria.
DR OrthoDB; 9769198at2; -.
DR Proteomes; UP000003781; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 8..386
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 388 AA; 42266 MW; 225CEB34276E654A CRC64;
MKAVCWHGSQ DVRVDNVPDP KILNPRDAII KVTSTAICGS DLHLYDGYIP TMQSGDILGH
EFMGEVVETG SEVKNLKKGD RVVVPFTISC GNCFFCNRDL WSLCDNSNPN AWMAEKFYGH
SPSGLFGYSH LLGGYAGGQA EYVRVPFADI GPLKVPESLS DEQVLFLTDI FPTGYMAAEN
CDIQPGEIVA VWGCGPVGQF AIRSALMLGA ERVIAIDRIP ERLALAEAGG AEILNYEEMD
AGVALKEMTG GRGPDCCIDA VGMEAHGTGV MAMYDTVKQA IRMETGRPLV LRQAIAACRK
GGKVSVPGVY GGFIDKMPMG AFVNKGLTMR SGQTHVHKYL RPLLERIEKG DIDPTFVITH
RLSLEEAPDA YKIFRDKKDN CIKVVLKP
//
