ID A3LR74_PICST Unreviewed; 368 AA.
AC A3LR74;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 24-JAN-2024, entry version 94.
DE SubName: Full=Zn finger-containing GTPase-Activating Protein for ARF {ECO:0000313|EMBL:ABN65687.2};
GN Name=GCS1 {ECO:0000313|EMBL:ABN65687.2};
GN ORFNames=PICST_30587 {ECO:0000313|EMBL:ABN65687.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN65687.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN65687.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
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DR EMBL; CP000497; ABN65687.2; -; Genomic_DNA.
DR RefSeq; XP_001383716.2; XM_001383679.1.
DR AlphaFoldDB; A3LR74; -.
DR STRING; 322104.A3LR74; -.
DR GeneID; 4837896; -.
DR KEGG; pic:PICST_30587; -.
DR eggNOG; KOG0704; Eukaryota.
DR HOGENOM; CLU_044516_2_0_1; -.
DR InParanoid; A3LR74; -.
DR OMA; FECEANN; -.
DR OrthoDB; 389572at2759; -.
DR Proteomes; UP000002258; Chromosome 3.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 8..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 136..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 40091 MW; 2FA738D581EF8784 CRC64;
MSIDPETRRK LLLLQKNGDN KKCADCGAPN PQWASPKFGI FICLECAGIH RGLGVHISFV
RSITMDQFKP EETLRMEKGG NEKIKTYFTA NGVDLTLPAK AKYDNYVAED YKELLTCEIE
GREFVAKDHS GKTLPTLDNL STSNNSSASI AQEQISSSRN TPVLQGEQKQ KNEAYFAQLG
SKNDSRPDHL PPSQGGKYGG FGNTPAPKPA AGGSLAGFTL DNLQADPLGT FSKGWGLFSS
TVAKSVNEVT ETVIKPGISQ LQESDITNEA KRAMAQFGQK MQETGKYGSE TFQTFTTEVN
ERGLNKTVED KFGKLFNNLS INQQEEKVPA AFGFSKPQEK TSLGSVSGGS KFGGAASKHE
DDDKWDDF
//
