ID A3LTM9_PICST Unreviewed; 398 AA.
AC A3LTM9;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:ABN66092.2};
DE Flags: Fragment;
GN Name=MFS42 {ECO:0000313|EMBL:ABN66092.2};
GN ORFNames=PICST_58666 {ECO:0000313|EMBL:ABN66092.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN66092.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN66092.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; CP000498; ABN66092.2; -; Genomic_DNA.
DR RefSeq; XP_001384121.2; XM_001384084.1.
DR AlphaFoldDB; A3LTM9; -.
DR STRING; 322104.A3LTM9; -.
DR GeneID; 4838416; -.
DR KEGG; pic:PICST_58666; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_000960_22_3_1; -.
DR InParanoid; A3LTM9; -.
DR OMA; IRHFGWR; -.
DR OrthoDB; 1703050at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF191; VACUOLAR BASIC AMINO ACID TRANSPORTER 4; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..391
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABN66092.2"
SQ SEQUENCE 398 AA; 43022 MW; 7179381F29CCD7AB CRC64;
TITMSDLIPL RDRGFYQGLA NVFFGLGSAS GGIIGGLVAD HLGWKYVFIL QVPLAVIVGL
ALYWNLNLPP GSPGLGAHGE DIKQKLKRVD FLGSFFLVSS LMCVLIAASL GGKEISYSSK
SFIGLCTASA LLLGGFIYTE AYISAEPIIP IELLGNRTVL SSSLANWFYT MGVFSYLFYV
PVYYTSVMDL TATQNGSRLI PNFFGVSLGS IGAGIYMKRT GRYYKLTVLV GIISIYGVLK
IFFINPNISL FEQFTLLLPS GLGYSCVLTV TLLSLIAAVP SKYQACTTSI QYTFRSTGST
LGVAVASALF QNVLRSNLTS KIHALIPDVN EANEIITKAL ANTNYTHEAP EIVRAAIRES
YALGCKGAFA VSVVTVSVGY FSSLFMREHK LHTSVNRD
//
