ID A3LZF3_PICST Unreviewed; 365 AA.
AC A3LZF3;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE RecName: Full=2-dehydropantoate 2-reductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PICST_63020 {ECO:0000313|EMBL:ABN68325.1};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN68325.1, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN68325.1, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
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DR EMBL; CP000501; ABN68325.1; -; Genomic_DNA.
DR RefSeq; XP_001386354.1; XM_001386317.1.
DR AlphaFoldDB; A3LZF3; -.
DR GeneID; 4840665; -.
DR KEGG; pic:PICST_63020; -.
DR eggNOG; ENOG502QWBM; Eukaryota.
DR HOGENOM; CLU_031468_2_1_1; -.
DR InParanoid; A3LZF3; -.
DR OMA; NNVWDQV; -.
DR OrthoDB; 1816688at2759; -.
DR Proteomes; UP000002258; Chromosome 7.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR21708:SF30; 2-REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00740)-RELATED; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002258}.
FT DOMAIN 5..178
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 212..331
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 365 AA; 41438 MW; FB1FD7907F8D967E CRC64;
MTKVLSIGLG GVGVMVAYTL HRNNGSKIDL TAVIRSDYDK VTKEGYTISS VDYGGRRENG
DANEAANQIT GFKPHNVVKS LEEIESGPFD YIIVSTKVIP KDDANNVWDQ VEKNKAKLLK
PDSKTSIVLI QNGIDIESYW SNLKDEATFI SGVSYISSTN NKGTITHFSH DSLVLGLFDI
SKIHDDTASA ALEKLIKLYS NDINTTKLDH NARYTRWKKL LYNATYNTVC CLCDLDVGKV
YELKDTDNII DEVIYPLMKE VQLVANRDLS KYDYGEYNQI IEERQVVNMI KDTEFYDAPT
YYQPSMLVDS RNGRLIELDI ILGNIIKLYK KNSEDNRGKI VQEIPYLNFL FLLLTMVQHR
LRGNQ
//
