ID A3VLZ7_9RHOB Unreviewed; 1569 AA.
AC A3VLZ7;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=RB2654_21183 {ECO:0000313|EMBL:EAQ10752.1};
OS Maritimibacter alkaliphilus HTCC2654.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Maritimibacter.
OX NCBI_TaxID=314271 {ECO:0000313|EMBL:EAQ10752.1, ECO:0000313|Proteomes:UP000002931};
RN [1] {ECO:0000313|EMBL:EAQ10752.1, ECO:0000313|Proteomes:UP000002931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2654 {ECO:0000313|EMBL:EAQ10752.1,
RC ECO:0000313|Proteomes:UP000002931};
RX PubMed=20729358; DOI=10.1128/JB.00873-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of Pelagibaca bermudensis HTCC2601T and Maritimibacter
RT alkaliphilus HTCC2654T, the type strains of two marine Roseobacter
RT genera.";
RL J. Bacteriol. 192:5552-5553(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ10752.1}.
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DR EMBL; AAMT01000026; EAQ10752.1; -; Genomic_DNA.
DR STRING; 314271.RB2654_21183; -.
DR eggNOG; COG0210; Bacteria.
DR eggNOG; COG0514; Bacteria.
DR HOGENOM; CLU_002862_0_0_5; -.
DR Proteomes; UP000002931; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd18018; DEXHc_RecQ4-like; 1.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000002931}.
FT DOMAIN 173..349
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 375..529
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 955..1170
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 976..983
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1569 AA; 173651 MW; 94311B7C9D1AC077 CRC64;
MFEVLRNQIE AFDALNTASP ETMLAYHWLT CRGMHSAGFD RLFSDIRGAA VPSEAEAHAA
IRALLKNAAC GAQVDAVLER LSDADLGWPM AYALAWISVA GGDSVMPPWV RAQFRDAARL
VKDLRDSNCR NPHCAYCAEH NDPTRALERW FGFPSFRPEP VDADGRPLQE KIVATAMEGE
HLLGILPTGT GKSICYQIPA LSRFDKTGAL TVVISPLVAL MADQVQGLVR AGISSAVTIN
GLLSLPERQD ALDKVRMGDA AILLISPEQL RSTTVRSVLA QREVGLWVLD EAHCVSKWGH
DFRPDYRYVS RFIKESSGDD PAPVLCLTAT AKPDVVQDIR SHFQERLGAE LTLLDGGASR
SNLSFQVLPT QRSTKLTDIL DAIEAGLPRE GASGAVVYCA TRSATERVAE FLKQQGIAAE
RYHAGLSADD KREIQEDFRV GNLRVIAATN AFGMGVDKPD IRLVVHGDVP GSLENYMQEA
GRAGRDRDPA QCVLLFNTED VDRQFSLSAR SRLARHEIGA ILKALRRLDV RTGKEGKIVA
TPGEIVHEEK DRDFQRDSNT DDTRVKTAVA WLEEAHLLNR EENRVQVFPA SLRVRSMAEV
REILAAADIT QRRRDDLTAI VQHIVNAPQE EGITTDELCG ISGLTVSGVR KALADLESLG
IAKDDTNITI FVHVRVENAS PKRFEAASRL EADLIEILRE QAPDAEIDEV LPCHLASVAQ
ALRERGHASV RPDIVEGLLR GIAQDGRDME GGRGNIGLRK ASKGSLMVRL QRSWAIIDQT
AQVRRQAAER LVTHLIEKVQ VGLKGKDVAV ETTLGDLLAA INSDALLRAS VNDPSKLMDR
ALLWLHEQQV VTLGKGLSVF RSAMTLHINK KGGGFTAHHF APLEDHYGEQ TIQTHVMAAY
AAKGMEDIET AQKLAHDYFA MDEADFMKAW MPGRMSEFRR QATPQTYAEI VDDLGNTTQA
QIVRDDREQT NVLVLAGPGS GKTRVLVHRV AYLVRIKRED PNGILVLAYN RHAAAEIRER
LRRLIGDDAR FVTVLTIHAL AMRLVGASFA GRAGAETPDF DTLLTDAARL LRGDGLDKVE
AEALRETLIQ GFRWILVDEY QDVGPEEYAL IAAVAGRSID DPDQRISLFA VGDDDQNIYS
FAGASVRHIR QFEADYSAKP VFLTDNYRSS GNIVSAANAV IEGARERMKT GHGITLDQSR
RKDPPGGVME KLDPVAQGRV QILACPAGNE AQALAAVDEM VRLSKLVPDW SWNRAAIISR
DWRKLLPVRD FAEALGIPVE MANENLPGVW RTREMQAFIR GLREGHGRMV SLGDLTDLLN
TIPSSRWTDQ IGEGLGVFAR EVDGKAIPSP DVIEWFAEWS RDSWGEQRGL KLLTAHRAKG
LEFDDVVIMD GGWERPSRNE DQDAPRRLFY VAMTRARRNL IVMSNDHHEY LPTMSPAVVT
RYVEPDIAAM PGPRRFFQSP EMRMVDLSFA GRQKDQHPVH RAISEATVGD AIQLKMAGGR
WQIEDMSGRV LGRMAKAFAP LGGTRFVSGQ IAAIIRRRKD DAGEKFHHML RREDWEVVVP
DLVFEQSKL
//
