ID   A3Y6X1_9GAMM            Unreviewed;       776 AA.
AC   A3Y6X1;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAQ67089.1};
GN   ORFNames=MED121_14219 {ECO:0000313|EMBL:EAQ67089.1};
OS   Marinomonas sp. MED121.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Marinomonas.
OX   NCBI_TaxID=314277 {ECO:0000313|EMBL:EAQ67089.1, ECO:0000313|Proteomes:UP000003436};
RN   [1] {ECO:0000313|EMBL:EAQ67089.1, ECO:0000313|Proteomes:UP000003436}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MED121 {ECO:0000313|EMBL:EAQ67089.1,
RC   ECO:0000313|Proteomes:UP000003436};
RA   Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA   Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA   Venter J.C.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAQ67089.1}.
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DR   EMBL; AANE01000001; EAQ67089.1; -; Genomic_DNA.
DR   RefSeq; WP_009832037.1; NZ_CH672429.1.
DR   AlphaFoldDB; A3Y6X1; -.
DR   STRING; 314277.MED121_14219; -.
DR   HOGENOM; CLU_020206_0_0_6; -.
DR   OrthoDB; 5777683at2; -.
DR   Proteomes; UP000003436; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.350; CHASE domain; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR006189; CHASE_dom.
DR   InterPro; IPR042240; CHASE_sf.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF03924; CHASE; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM01079; CHASE; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          371..506
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          515..769
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   776 AA;  88268 MW;  5B606C0E1ADB5EDA CRC64;
     MLKGRYLKQA HLIVFFFVFL CALIVLFSLL REDGKRIAAN QQLASMQLEE SILSSLNAYE
     LDVTGLAAFF HASEFVSNHE FDTFSQTLIN HQRTPIYNSF FAQSVLHQNK SAFVDQQIER
     DKGAFQILPE GQRREYLPIT YAFPDKRFLG FDTLEPDVFL LNRTTQDWNN RQVKLLKPSA
     SNPDVTIGQF ETPGFYVLSK NVYQDVNDRS SNKENWLGVV AVSFDVASVL QSFNAKFDHD
     LLFRLSDLEN ANASKKYFYL SHPADFDQWQ NKSFMGTEIL YGGRVWLLET AYLGSSIALY
     DWNTILLPVV SLVLLAIFLS VYIRSLNTSF LSMMRRVNRQ LEIDDLTNLY SRYFIHEKLD
     KAIIRCKEKQ TNLAVVFMDL DHFKTVNEAF GHEVGDKLLN KVAQRLTSVW PADAVLGRLG
     GDEFLAFIEL NEQMNHQDLK LLCREVITQV SHSYLIDSRT LTIGCSIGVA LFPNFGSDAM
     TLVKNADMAM YKAKALGRSI YHFYDGDIGD RLARNVKIET RLRHAMQNDG LKLYFQPKVN
     LESLECIGLE ALLRWRDEEL GVVSPAEFIP IAEQSGIILP LGEWVIDQTC RQIFNWQAQG
     LSVPPIAINC SAAQLKRDDF FSVLLQSLNR YDISPSQVEL EVTESMLIED AERCSKLLQQ
     VSRLGVKITI DDFGTGYSSL SYLKDLPFNC IKIDQVFIRD MIEDVNHAAI TAAIIKMSQT
     LNLQVVAEGI TNHKQLEVLR ELGCNIGQGF LFGEAFHADH LAVNDEKIRK SLLAED
//