ID A4BIE9_9GAMM Unreviewed; 369 AA.
AC A4BIE9;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 96.
DE SubName: Full=Alanine racemase {ECO:0000313|EMBL:EAR08156.1};
DE EC=5.1.1.1 {ECO:0000313|EMBL:EAR08156.1};
GN Name=alr {ECO:0000313|EMBL:EAR08156.1};
GN ORFNames=MED297_00670 {ECO:0000313|EMBL:EAR08156.1};
OS Reinekea blandensis MED297.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Reinekea.
OX NCBI_TaxID=314283 {ECO:0000313|EMBL:EAR08156.1, ECO:0000313|Proteomes:UP000005953};
RN [1] {ECO:0000313|EMBL:EAR08156.1, ECO:0000313|Proteomes:UP000005953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MED297 {ECO:0000313|EMBL:EAR08156.1,
RC ECO:0000313|Proteomes:UP000005953};
RA Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R.,
RA Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600821-50};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR08156.1}.
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DR EMBL; AAOE01000025; EAR08156.1; -; Genomic_DNA.
DR RefSeq; WP_008046449.1; NZ_CH724153.1.
DR AlphaFoldDB; A4BIE9; -.
DR STRING; 314283.MED297_00670; -.
DR HOGENOM; CLU_028393_2_1_6; -.
DR OrthoDB; 9813814at2; -.
DR Proteomes; UP000005953; Unassembled WGS sequence.
DR GO; GO:0008784; F:alanine racemase activity; IEA:UniProtKB-EC.
DR GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR020622; Ala_racemase_pyridoxalP-BS.
DR InterPro; IPR029066; PLP-binding_barrel.
DR NCBIfam; TIGR00492; alr; 1.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00395; ALANINE_RACEMASE; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:EAR08156.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR600821-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000005953}.
FT DOMAIN 241..369
FT /note="Alanine racemase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01005"
FT BINDING 136
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT BINDING 310
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-52"
FT MOD_RES 40
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ SEQUENCE 369 AA; 40554 MW; 0540EACFDC3C23EF CRC64;
MSSDVIHTAW CEILTDRIAN NLSLALSLLP EHAEFCAVLK ADAYGHGIAE VAAIVCEHRI
KTVGITSNAE ARLVREAGFE GTILRLRTAT PSEIAGAVAD RVQEQVSSLY TAEVIDSLTE
HSEGVHLAIN AGGMSRDGLE LNERDGHDTC QRIVDLLGDR IVGICTHHPS GSEQDLQLSD
QHFRSDLNWI FSNTALKREQ VNVHAGSSLS LISSTPIETD FYRCGAILYG ILKPELGFEH
TMQLKAQITN ITTYPQGSTI GYDRTTTLTR DSRVANIALG YANGFRRNYF GRSHVLIRGQ
LVPVLGKVSM NTIVADVTDI PVVEVEDEVV IFGHQGTGKI DIKRIEMQAD TIMADIYAEW
GQRNPRVYI
//
