ID A4F0C9_9RHOB Unreviewed; 337 AA.
AC A4F0C9;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=2-oxoisovalerate dehydrogenase, E1 component, beta subunit {ECO:0000313|EMBL:EBA14752.1};
GN ORFNames=RSK20926_01957 {ECO:0000313|EMBL:EBA14752.1};
OS Roseobacter sp. SK209-2-6.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseobacter.
OX NCBI_TaxID=388739 {ECO:0000313|EMBL:EBA14752.1, ECO:0000313|Proteomes:UP000005964};
RN [1] {ECO:0000313|EMBL:EBA14752.1, ECO:0000313|Proteomes:UP000005964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK209-2-6 {ECO:0000313|EMBL:EBA14752.1,
RC ECO:0000313|Proteomes:UP000005964};
RA Ward B., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EBA14752.1}.
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DR EMBL; AAYC01000016; EBA14752.1; -; Genomic_DNA.
DR RefSeq; WP_008209436.1; NZ_AAYC01000016.1.
DR AlphaFoldDB; A4F0C9; -.
DR eggNOG; COG0022; Bacteria.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000005964; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005964}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 337 AA; 36486 MW; 5BE67D0C56651999 CRC64;
MASMTMIEAI REAHDVAMAA DDKVVVYGED VGFFGGVFRC TAGLQEKYGK SRCFDAPINE
SGIVGTAIGM AAYGLKPVIE IQFADYVYPA YDQIVSEAAR LRHRSNGDFT CPIVIRMPTG
GGIFGGQTHS QSPEALFTHV SGLKVVMPSN PADAKGLLLA SIADPDPVIF LEPKRLYNGP
FDGHHDKPLV SWKKHPLGDV PDGSDAVPLG KAKIRREGAD LTILAYGTMV YVAEAAVAET
GIDAEVIDLR SLMPLDLETI VASVQKTGRC VIVHEATRTC GFGAELMSLV QESCFYHLEA
PIIRVTGWDT PYPHAQEWEY FPGPARLGEA LNKVMED
//
