ID A4F5V5_SACEN Unreviewed; 561 AA.
AC A4F5V5;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Glycine betaine transporter, BCCT family {ECO:0000313|EMBL:CAL99429.1};
GN OrderedLocusNames=SACE_0076 {ECO:0000313|EMBL:CAL99429.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99429.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAL99429.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BCCT transporter (TC 2.A.15) family.
CC {ECO:0000256|ARBA:ARBA00005658}.
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DR EMBL; AM420293; CAL99429.1; -; Genomic_DNA.
DR RefSeq; WP_009949867.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4F5V5; -.
DR STRING; 405948.SACE_0076; -.
DR KEGG; sen:SACE_0076; -.
DR eggNOG; COG1292; Bacteria.
DR HOGENOM; CLU_010118_4_0_11; -.
DR OrthoDB; 9775735at2; -.
DR Proteomes; UP000006728; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR InterPro; IPR018093; BCCT_CS.
DR InterPro; IPR000060; BCCT_transptr.
DR NCBIfam; TIGR00842; bcct; 1.
DR PANTHER; PTHR30047:SF7; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30047; HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF02028; BCCT; 1.
DR PROSITE; PS01303; BCCT; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 523..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 59846 MW; 160C277895313E4A CRC64;
MTDHPRTDWV VFGVTAAIMF GLVSWGVLAT DSLSTSSQAA FSWMMSNLGW GFVLAATGFV
VFALFLAFSR YGRIPLGQDG EKPEFRTISW IAMMFSAGMG IGLMFYGVSE PLSHFVDPPP
GSVPGETDEA IKTAMATSLF HWTLHPWAIY AVAGLAIAYS SFRRGRKQLI SAVFLPLIGK
RNAEGPIGRL IDILALFATL FGSAASLGIG TLQIKSGMQA ANWIGETGTT ILVLIIVVLT
ICFIASAVSG VAKGIQWLSN INMVLAALLA VFVFVVGPTV FILNLLPTTL GSYLSDFGEM
ASRAGATGGP DMLDWLSSWT VFYWAWWISW TPFVGMFIAR ISRGRTIRQF IGGVLLVPSV
VSLVWFAIFG GAAINTQQGG QPVYGDGSAE AQTFDVLAHM PLTLVTSVLV MVLVAIFFVS
GADAASVVMG TLSQRGSIEP SKWVVIFWGA ATGAVAAIML VIGGGQETAL QGIQNLTFIG
ALPFAIIMVL MCVALMRDLR SDRITLREEK GAEVLEQAVI IGTEEHDGDF QLEVSPAEPS
ENGDESEDDA DSKAKSASGS E
//
