ID A4F8U7_SACEN Unreviewed; 399 AA.
AC A4F8U7;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Transcriptional regulator with XRE-family HTH domain {ECO:0000313|EMBL:PFG94267.1};
DE SubName: Full=Transcriptional regulator, XRE family {ECO:0000313|EMBL:CAM00472.1};
GN OrderedLocusNames=SACE_1141 {ECO:0000313|EMBL:CAM00472.1};
GN ORFNames=A8924_1538 {ECO:0000313|EMBL:PFG94267.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00472.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM00472.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM00472.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG94267.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG94267.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AM420293; CAM00472.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG94267.1; -; Genomic_DNA.
DR RefSeq; WP_009946520.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4F8U7; -.
DR STRING; 405948.SACE_1141; -.
DR KEGG; sen:SACE_1141; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG1396; Bacteria.
DR HOGENOM; CLU_033540_1_0_11; -.
DR OrthoDB; 3504495at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR46797; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR46797:SF1; METHYLPHOSPHONATE SYNTHASE; 1.
DR Pfam; PF13560; HTH_31; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT DOMAIN 11..66
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 399 AA; 43130 MW; 8810252FA5EC1B68 CRC64;
MVTEGPIGER IRIYRQRRGL SQKELAHLVG RSESWLSQVE RGIRSVDRLS VLVDVARVLK
TDVETLAGYR MAYAPNGQPE LEGLEDIRQA MSAYAGLGLS RTPTSSVAEI ASLTTEVHQR
YQAADYAAAA RILPGLITAS DAVVSESGSA DLRAALSVQS QAYVAAAKLV TKIGDGQLAW
IAADRAVTAA MRADSDILKA MAAYQVACAF LKTDRIDQAE HVAITTAENF ADDSPDGLSV
QGALFLIGAV IAGRRSDRPE ATDRLRRAQY LADALGYDGN HGWTAFGPTN VAIHQISAAA
ELGDAKLAIA RAEDVETDGL PDGLRSRRAQ VFIDTAWAYS QHRDDAAVVV NLMEAERTAP
QALRYNVIVR EMLRELLKRE RRSATPGLRA LAKRSGVLH
//
