ID A4FB74_SACEN Unreviewed; 325 AA.
AC A4FB74;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:CAM01299.1};
DE EC=4.6.1.1 {ECO:0000313|EMBL:CAM01299.1};
GN Name=cya {ECO:0000313|EMBL:CAM01299.1};
GN OrderedLocusNames=SACE_1989 {ECO:0000313|EMBL:CAM01299.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM01299.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM01299.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
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DR EMBL; AM420293; CAM01299.1; -; Genomic_DNA.
DR AlphaFoldDB; A4FB74; -.
DR STRING; 405948.SACE_1989; -.
DR KEGG; sen:SACE_1989; -.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_043761_2_0_11; -.
DR Proteomes; UP000006728; Chromosome.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR032026; Ad_Cy_reg.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR Pfam; PF16701; Ad_Cy_reg; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CAM01299.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT DOMAIN 167..276
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 325 AA; 35317 MW; 911D97E5A5E9C905 CRC64;
MSEPRDEAVA GRPELETVLL GGPARHTKAD VAREAGVELR RAERLWQAMG FAHVDDDAVV
FTDADVAALR RLVQLVSAQV LTPEAETAVA RSLGQAMSRL AEWQVGIFRT VLGDDFSGDL
ATTAQFAGAI MPVMEQLQGY VWRRHLTATA MRELGGRDTG EDERTLVIGF ADIVGYTRLI
RDFTELELAS LIDDFEELAT GVVAENRGRI IKTVGDEVLF VTDTAADAAE VALSLNEQIA
ESTRLPPLRI GLAKGVVLAR FGDVYGSTVN IASRLTSVAR PASVLVDREV SGSLRDHPDY
HLVSVGPTKV QGFRGLRAWA LRRAR
//
