ID   A4FJW9_SACEN            Unreviewed;      1025 AA.
AC   A4FJW9;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51192};
GN   OrderedLocusNames=SACE_5087 {ECO:0000313|EMBL:CAM04344.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM04344.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAM04344.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
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DR   EMBL; AM420293; CAM04344.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4FJW9; -.
DR   STRING; 405948.SACE_5087; -.
DR   KEGG; sen:SACE_5087; -.
DR   eggNOG; COG1204; Bacteria.
DR   HOGENOM; CLU_274274_0_0_11; -.
DR   Proteomes; UP000006728; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR   PANTHER; PTHR47961:SF6; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN          151..326
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
SQ   SEQUENCE   1025 AA;  113136 MW;  C5BFC81A5E9AD22C CRC64;
     MALRAGVAFL GLDVARIGQL LRVWRTEAAA MASRIEMDSL QSTMFGPAEA VTRAVAELMA
     FLRYGNRERL RAARAGLHSV IDLRAGGGDH DARWVTAHLL AIADGMETSS IWSVLPDGTP
     DAVAQAFTVG APPVLTLWPP QRDLLMRTTA NPLEPATTRL LLSVPTSAGK TLLAQILICH
     HLATQPGDVC YVTPLRSLGR EMRQALSGRL RVLQKGLGAD LPDFGAISID DFFTFIDESG
     DSSVEVMTPE RLAHLLRRDP EGVLDRFSMF VIDEAHLLAQ QDRGFLLEWL LAVLATTDAR
     LILLSGVMGN ADKVAAWLDP TRPDVLFSSD WRGPRRLHAL LYSDVVWEAE QRLPLKSKTF
     TSRSSYPVIA DLRVRPAESN VQRLTTPRDE PIGEMESKRR TNGTYERNRT PFYLLCARTA
     HVLLPTGSLL MILSRRDYAR NAAQEVAKRL DVTSRTEALR EFLEERLGVQ HPLVDCVLHG
     VAYHHAGLPV DVLDALEQAM RSEVLLAMFA TSTLTDGVNL PVRTVLICET RYQGQDPGQQ
     MDGPRLLNAV GRAGRAGRET EGWIVLGVQA KPADRHFEVL QPAADDLEIV STLHSNDALH
     QLAEAEALIA ETADALFELA SGAAADFATF VWFVLSTLER LDPWASATDP RDVVRRLLAF
     TQMPDHIERR WMAFANHVEQ QYARTPAESR RRWTVTGTAL RSARRIEQIA VKVADEVTAR
     HEDLPQADSG MTSLTTMSLT TEEALAVFDD AGIFELLLEL PEAGKVWRFK PTVGAKTTVD
     VSVASALRGW LAGLDMPALA AAILPTVDNP SWRLEQTVDA VSGAFEHFLS WTVGVVVSQA
     NELLVERGSA TVLPEDLSYF IRYGVDTTTA LKLLTSGVKS RRIAHQIGRK AQAQDIEWRE
     VRDWLRNLHI AGWRHDFEAT PREIEDLAEF CRSPARSPLR QLLEDHETTV DLARPLDFLP
     TSPRAVELRM PSPSAPVEVW TVDSPASRIG IIAAASHADI HLLHSSGVEC SATTDGIVVR
     LREAD
//