ID A4G8R7_HERAR Unreviewed; 329 AA.
AC A4G8R7;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase) {ECO:0000313|EMBL:CAL62904.1};
DE EC=2.5.1.- {ECO:0000313|EMBL:CAL62904.1};
GN Name=ispB {ECO:0000313|EMBL:CAL62904.1};
GN OrderedLocusNames=HEAR2788 {ECO:0000313|EMBL:CAL62904.1};
OS Herminiimonas arsenicoxydans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Herminiimonas.
OX NCBI_TaxID=204773 {ECO:0000313|EMBL:CAL62904.1, ECO:0000313|Proteomes:UP000006697};
RN [1] {ECO:0000313|EMBL:CAL62904.1, ECO:0000313|Proteomes:UP000006697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ULPAs1 {ECO:0000313|Proteomes:UP000006697};
RX PubMed=17432936; DOI=10.1371/journal.pgen.0030053;
RA Muller D., Medigue C., Koechler S., Barbe V., Barakat M., Talla E.,
RA Bonnefoy V., Krin E., Arsene-Ploetze F., Carapito C., Chandler M.,
RA Cournoyer B., Cruveiller S., Dossat C., Duval S., Heymann M., Leize E.,
RA Lieutaud A., Lievremont D., Makita Y., Mangenot S., Nitschke W., Ortet P.,
RA Perdrial N., Schoepp B., Siguier N., Simeonova D.D., Rouy Z., Segurens B.,
RA Turlin E., Vallenet D., Van Dorsselaer A., Weiss S., Weissenbach J.,
RA Lett M.C., Danchin A., Bertin P.N.;
RT "A tale of two oxidation states: bacterial colonization of arsenic-rich
RT environments.";
RL PLoS Genet. 3:518-530(2007).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CU207211; CAL62904.1; -; Genomic_DNA.
DR AlphaFoldDB; A4G8R7; -.
DR STRING; 204773.HEAR2788; -.
DR KEGG; har:HEAR2788; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_0_4; -.
DR OrthoDB; 9805316at2; -.
DR Proteomes; UP000006697; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF87; OCTAPRENYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000006697};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:CAL62904.1}.
SQ SEQUENCE 329 AA; 35535 MW; 7F1DA86F8962B7F0 CRC64;
MASPSTTSAQ NLLIQPIAAD MSAVDAVIRQ KLHSEVALVN QIADYIISAG GKRIRPVLVL
LMANALGYRG THQYDLAAVV EFIHTATLLH DDVVDESELR RGRKTANALF GNAASVLVGD
FLHSRAFQMM VTVGNIRAMQ ILADATNVIA EGEVLQLLNM HDPDISEERY TQVIRSKTAK
LFEAAAQLGA LIAGASEDEI EAAAEYGRSL GTAFQLIDDV LDYSGHAEDI GKNVGDDLRE
GKATLPLIYL MEHGNTEQRE LVRSCIENGD EEHFDAVLLA VTTSGALDYT KRKAEEAAAR
AAASIAGLPE SQFKDALLNL SSFAVHRNH
//
