ID A4HCY0_LEIBR Unreviewed; 464 AA.
AC A4HCY0;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Leucine-rich repeat protein (LRRP) {ECO:0008006|Google:ProtNLM};
GN ORFNames=LBRM_23_1190 {ECO:0000313|EMBL:CAM36626.1};
OS Leishmania braziliensis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania;
OC Leishmania braziliensis species complex.
OX NCBI_TaxID=5660 {ECO:0000313|EMBL:CAM36626.1, ECO:0000313|Proteomes:UP000007258};
RN [1] {ECO:0000313|EMBL:CAM36626.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM36626.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM36626.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM36626.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR798998; CAM36626.1; -; Genomic_DNA.
DR RefSeq; XP_001565191.1; XM_001565141.1.
DR AlphaFoldDB; A4HCY0; -.
DR STRING; 5660.A4HCY0; -.
DR GeneID; 5415765; -.
DR KEGG; lbz:LBRM_23_1190; -.
DR VEuPathDB; TriTrypDB:LbrM.23.1190; -.
DR VEuPathDB; TriTrypDB:LBRM2903_230021400; -.
DR InParanoid; A4HCY0; -.
DR OMA; MRCVSKP; -.
DR Proteomes; UP000007258; Chromosome 23.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR SMART; SM00367; LRR_CC; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007258}.
SQ SEQUENCE 464 AA; 51374 MW; 6DBE14743050C584 CRC64;
MRYIPYNRRT LTSMRCVSRP FRSAVQSPHS PWAQHKEIMV SRYGQCIIFN AQENEEGHSN
FSLYSISSIG RKFRTHSAKL LGRYHALVAN GLSRLVLHHA PVENSFFEPL GALTNLRELE
LVSCRGVTSV GGASRIKGLE SLTVVFCPVE SDGVTGLRLS KLKKLTLRSC SKLSNLNAIH
SETCASLVDV HVESCGVYDD TSSAFFGYLS ANLRTLNLTS TFIDTALTHI PTAALESLTS
LLVPETPFHS STLNSLKVSL AKKLEHLSLE GCEEITELSA LGSLTKLRFL DVSRLSVLQD
IECVAQCTEL EMFRCAGTDL NSIAFLKNMR HLRVLDATNT ALTDYTLIHL EESPELDTVV
LTGCLYISSI NAFHQCPKIR RILCGRTAVT NEGVEMLTEC AALEELDLKM TNVTDVNRLA
DCPFLKAINV CGSIMMQDAI QRLLDKSSVE VICDSFEEND YMDC
//
