ID A4HXL6_LEIIN Unreviewed; 802 AA.
AC A4HXL6;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=IQ_calmodulin-binding_motif_containing_protein_-_putative {ECO:0008006|Google:ProtNLM};
GN ORFNames=LINJ_17_1500 {ECO:0000313|EMBL:CAM59835.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM59835.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM59835.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM59835.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM59835.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM59835.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR796449; CAM59835.1; -; Genomic_DNA.
DR RefSeq; XP_001464807.1; XM_001464770.1.
DR AlphaFoldDB; A4HXL6; -.
DR STRING; 5671.A4HXL6; -.
DR GeneID; 5068211; -.
DR KEGG; lif:LINJ_17_1500; -.
DR VEuPathDB; TriTrypDB:LINF_170021200; -.
DR eggNOG; ENOG502S041; Eukaryota.
DR InParanoid; A4HXL6; -.
DR OMA; AEGHFIM; -.
DR Proteomes; UP000008153; Chromosome 17.
DR Gene3D; 1.20.5.190; -; 2.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR10699; NEUROMODULIN; 1.
DR PANTHER; PTHR10699:SF11; ZGC:153721; 1.
DR Pfam; PF00612; IQ; 3.
DR SMART; SM00015; IQ; 6.
DR PROSITE; PS50096; IQ; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
FT REGION 394..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..417
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 90400 MW; E682E52676B0AA21 CRC64;
MHHVRHLSPP SLAPSIFFYA FWPHADRQET QTSACCPVSL SFIHTCTHER LSCAEVHRTA
LSPSFPIAAR AYADHPARAW KKDSAAFHRG ALRTPDEVAA MTNFSPVKCE MDGLSPAAGT
DGNPLAQPFW QSSRSSLPTF DVHGRGTARG RLQNPAHIDS IHRSEGSRVG QDTCRYMQAA
AASSQKAVHQ LLSRLQTYRS FKPFLSPPAP YRDNFFTHDR GFSSFSGPSH GRLSTATVSR
DQLWQMVDGI LDTSVAQLLQ HNAEGHFIMT LQSALGLEAP ISTAKSGTVI ESRKAATPAI
NGGATELASE ERTPAGGPRQ PLPPALQKTA VMSSFAPASA LANRWALDHP SATTAAVEEQ
HHAWATFDQQ RQRTSRCFYL QAMQEQLDVL QAEQARDAAD TTHSPPNRGD DSHSYLLDVH
SSSDSEDAVT KAEEEKQQAL WRTFQDGPVL TVGASESPRE TALGVPGIVS DYLESTDLQD
WLHCSWAHRT HRHESAALRI QCAYRVYRAR CKVREMRYER RQAFLASLSA ERKARQVWDL
ALQVQKDTTT TTTSGTDSTL RALQFFINKV NAVVAKHRAR KQYQQKQDAE IRRYAATRIQ
AVYRGHRTRV FVTELRHPEI VALRKQLQQE NCAKLIQTCW RRYAAQRHWR LARHAACVLQ
SMYRCHAARR MLAERRYQRN LEASAELTKF AVQRIERWYG SVLAARNAIG RAHVAELLVL
QRVCRGYQGR HGVQEEKRLS RLRSAVRTIE QRRWRVMEAR EAIERRAALS TANAAKRIAS
MRDDAAVTIQ RAWRRRCVLH VC
//
