ID A4IGY5_XENTR Unreviewed; 484 AA.
AC A4IGY5;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=Vim protein {ECO:0000313|EMBL:AAI35298.1};
DE Flags: Fragment;
GN Name=vim {ECO:0000313|EMBL:AAI35298.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI35298.1};
RN [1] {ECO:0000313|EMBL:AAI35298.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole embryo {ECO:0000313|EMBL:AAI35298.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Vimentins are class-III intermediate filaments found in
CC various non-epithelial cells, especially mesenchymal cells. Vimentin is
CC attached to the nucleus, endoplasmic reticulum, and mitochondria,
CC either laterally or terminally. {ECO:0000256|ARBA:ARBA00002825}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; BC135297; AAI35298.1; -; mRNA.
DR AlphaFoldDB; A4IGY5; -.
DR HOGENOM; CLU_012560_7_4_1; -.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF5; VIMENTIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}.
FT DOMAIN 122..430
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 112..263
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 321..408
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAI35298.1"
SQ SEQUENCE 484 AA; 55459 MW; 3AB0CCB2BFFF10AA CRC64;
EGCSHRNSSV QGITKETQSL STTMATTKSS YRRIFGGNPR SSSSGNRYVT SSTRYSLGSA
MRPGAGSSSS RVVYSTSASP AVFKSSSVRL RSSLPPARLA DTVDFTLADA VNLEYKANRT
NEKAEMQELN DRFANFIDKV RFLEQQNKIL VAELEQLKGK GTSRIGDLYE EEMRELRRQL
DQVTNAKDRV EVDRDNLADD LQRLREKLQD EMIQKEEAEG NLQSFRQDVD NASLARIDLE
RKVESLQEEI VFLKKLHDEE IRELQLQIQE SHIQVDMDVS KPDLTAALRD VRQQYENVAA
KNLSDAEDWY KSKFADLSEA ANRNNDALRQ AKQDANDYRR QIQTLTCEID AMKGSNESYE
RQMREMEENF AGEAANYQDT IQRLQEEIHN MKEEMARHLR EYQDLLNVKM ALDIEIATYR
KLLEGEESRI TVPVHSFSSM SLRETNLDSH PVESHSKRTL LIKTVETRDG QVINESSQHH
DDLE
//
