ID A4JYP0_DANRE Unreviewed; 436 AA.
AC A4JYP0;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=cDNA, clone cssl:d0214 {ECO:0000313|EMBL:CAM73222.1};
GN Name=dhrs13b.2 {ECO:0000313|RefSeq:NP_001077299.1,
GN ECO:0000313|ZFIN:ZDB-GENE-080303-14};
GN Synonyms=sc:d214 {ECO:0000313|RefSeq:NP_001077299.1}, sc:d818
GN {ECO:0000313|RefSeq:NP_001077299.1}, zgc:198241
GN {ECO:0000313|RefSeq:NP_001077299.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:CAM73222.1};
RN [1] {ECO:0000313|EMBL:CAM73222.1}
RP NUCLEOTIDE SEQUENCE.
RA Bushell K.M., Sollner C., Bockett N., Wright G.J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:NP_001077299.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=29471808;
RA Grimholt U.;
RT "Whole genome duplications have provided teleosts with many roads to
RT peptide loaded MHC class I molecules.";
RL BMC Evol. Biol. 18:25-25(2018).
RN [4] {ECO:0000313|RefSeq:NP_001077299.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=29692779;
RA Wu X.M., Chen W.Q., Hu Y.W., Cao L., Nie P., Chang M.X.;
RT "RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen
RT Presentation but Not for MAPK and PI3K/Akt Pathways.";
RL Front. Immunol. 9:726-726(2018).
RN [5] {ECO:0000313|RefSeq:NP_001077299.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=29872545; DOI=10.1038/s41536-018-0049-0;
RA King B.L., Rosenstein M.C., Smith A.M., Dykeman C.A., Smith G.A., Yin V.P.;
RT "RegenDbase: a comparative database of noncoding RNA regulation of tissue
RT regeneration circuits across multiple taxa.";
RL NPJ Regen Med 1 3:10-10(2018).
RN [6] {ECO:0000313|RefSeq:NP_001077299.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CU458961; CAM73222.1; -; mRNA.
DR RefSeq; NP_001077299.1; NM_001083830.1.
DR GeneID; 559844; -.
DR KEGG; dre:559844; -.
DR AGR; ZFIN:ZDB-GENE-080303-14; -.
DR CTD; 559844; -.
DR ZFIN; ZDB-GENE-080303-14; dhrs13b.2.
DR OrthoDB; 4220387at2759; -.
DR Proteomes; UP000000437; Alternate scaffold 15.
DR Proteomes; UP000000437; Chromosome 15.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd05771; IgC1_Tapasin_R; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23411:SF45; CDNA, CLONE CSSL:D0214-RELATED; 1.
DR PANTHER; PTHR23411; TAPASIN; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF07686; V-set; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS00290; IG_MHC; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 403..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..271
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 290..393
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 436 AA; 49313 MW; A5F5F05C68A0C594 CRC64;
MIVLRTRIHN MFWTIGGFIL ALVCLGVNGS QSLRDVQWLP CQFVDEKVQI NEEGHTETKY
IHRESVLRFG KDGDSALHPA ITFLVTGSKV DMRRYLEGSE DTLQCEIRRY STGGIVMRWP
VAGAQEYDVW FTCTLRHTQG LFVITSFLRY TPAAPAQGQV DFLQWMSVSD RDLLTTTAAM
VVLTRTPSVE VGFLKEPELH CQFAVDHKLP NATVEWRLQR HGERTKLFSY SSRTGKSEGK
GVTVKTIAGG NASFKLEPTR KHSEGTYVCS VMVPPLYGSH DIPLSLSEQP RVSLNVGSTL
SMVIGQDQKL ICEAESYYPL DVDIEWYREP HGGSPTPLFL KNVLYSSHRI HQDGTYSLSA
FFYLQPGLED SGYKYTCRVS HKSLLTPVRK SFYLVATEPD STMWYIAVFG FIIAMLVILC
YMLPQVLAGR RSKKMF
//
