ID   A4MZ20_HAEIF            Unreviewed;       243 AA.
AC   A4MZ20;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Exonuclease III {ECO:0000313|EMBL:EDJ88333.1};
DE            EC=3.1.11.2 {ECO:0000313|EMBL:EDJ88333.1};
GN   ORFNames=CGSHi22121_09905 {ECO:0000313|EMBL:EDJ88333.1};
OS   Haemophilus influenzae 22.1-21.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=374927 {ECO:0000313|EMBL:EDJ88333.1, ECO:0000313|Proteomes:UP000004131};
RN   [1] {ECO:0000313|EMBL:EDJ88333.1, ECO:0000313|Proteomes:UP000004131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=22.1-21 {ECO:0000313|EMBL:EDJ88333.1,
RC   ECO:0000313|Proteomes:UP000004131};
RX   PubMed=17550610; DOI=10.1186/gb-2007-8-6-r103;
RA   Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C.,
RA   Ehrlich G.D.;
RT   "Characterization and modeling of the Haemophilus influenzae core and
RT   supragenomes based on the complete genomic sequences of Rd and 12 clinical
RT   nontypeable strains.";
RL   Genome Biol. 8:R103.1-R103.18(2007).
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DR   EMBL; AAZD01000003; EDJ88333.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4MZ20; -.
DR   Proteomes; UP000004131; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008311; F:double-stranded DNA 3'-5' DNA exonuclease activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR   InterPro; IPR011527; ABC1_TM_dom.
DR   InterPro; IPR036640; ABC1_TM_sf.
DR   PANTHER; PTHR11384:SF59; ATP-BINDING CASSETTE SUB-FAMILY D MEMBER; 1.
DR   PANTHER; PTHR11384; ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER; 1.
DR   Pfam; PF06472; ABC_membrane_2; 1.
DR   SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000313|EMBL:EDJ88333.1};
KW   Hydrolase {ECO:0000313|EMBL:EDJ88333.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Nuclease {ECO:0000313|EMBL:EDJ88333.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          50..225
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000259|Pfam:PF06472"
SQ   SEQUENCE   243 AA;  28369 MW;  DBE81C8C73A2C384 CRC64;
     MDYSQEAITS LIWILQTLAI TSVVFSFGIF LLVRFTQWGK QFWMFAGGYL SPKRSIKPIL
     FFLLIVAMTL LSVRISLVNS EWYKNMYTSL QEFNEHVFWQ QMGLFCVIAA SSVSAALVSY
     YLEQRFVINW IEWLNEQLVN KWMAHRAYYK TQYLSENLDN PDQRIQQDVQ SYVKTTLSLS
     TGVIDAVTSM ISYTILLWGL AGPMIVLGVE IPHMMVFFSV WLCHFHNPHR ILARSPINLI
     EFY
//