ID A4SK45_AERS4 Unreviewed; 556 AA.
AC A4SK45;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Molecular chaperone, hsp70 family {ECO:0000313|EMBL:ABO89267.1};
GN Name=hscC {ECO:0000313|EMBL:ABO89267.1};
GN OrderedLocusNames=ASA_1146 {ECO:0000313|EMBL:ABO89267.1};
OS Aeromonas salmonicida (strain A449).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=382245 {ECO:0000313|EMBL:ABO89267.1, ECO:0000313|Proteomes:UP000000225};
RN [1] {ECO:0000313|Proteomes:UP000000225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A449 {ECO:0000313|Proteomes:UP000000225};
RX PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA Brown L.L.;
RT "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT the evolution of a fish pathogen.";
RL BMC Genomics 9:427-427(2008).
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR EMBL; CP000644; ABO89267.1; -; Genomic_DNA.
DR RefSeq; WP_005317064.1; NC_009348.1.
DR AlphaFoldDB; A4SK45; -.
DR STRING; 29491.GCA_000820065_02080; -.
DR KEGG; asa:ASA_1146; -.
DR PATRIC; fig|382245.13.peg.1144; -.
DR eggNOG; COG0443; Bacteria.
DR HOGENOM; CLU_005965_2_4_6; -.
DR Proteomes; UP000000225; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10235; HscC_like_NBD; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR042030; HscC_NBD.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00012; HSP70; 2.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322}.
SQ SEQUENCE 556 AA; 62336 MW; A49AE623089043C3 CRC64;
METLRPAIGI DLGTTNSAIA VWQDGKAYLI PNAHGQDLTP SIVCIGDDNT LLVGQAAATR
LLTDPSNTAS HFKRFLGSER RYRLGKEQYT PTELCALVLG SLKADAEVWL GHEVYEVVIS
VPAYFGDQQR KQVRLAADLA GLDAVRLINE PTAAAMAYSL HEQHSRRFLV FDLGGGTFDV
TVVEYQDGIM EVRASAGDNR LGGEDFTQDL VDAVLDQLGT DRSDMPLSQL GLVYLASERA
KRHRSGSCLE VELGGEWNRT LRFSEIELAG IWRETLNRLR KPLSQALSDA RLHPEEVDEL
IFVGGASRQS EVQQTAVRLL GRFGRHDLDP DRVVAIGAAI QAACRLRDSA VEELIMTDVC
PFTLGIEVSQ GDQHGIFSPI LERNTVVPAS RVERYRSGHE QQKAVSISIY QGERFWVRDN
LHVDNLEIPL PTGKGIQEVD VRFSYDINGM LEVDVTLVST GELFQKVIDR SPAGVTEERK
RESRERLARL KHHPRDALPN LTLSERLEQL YEESTGNERR QIEQWLLQFE RVLAGQDPQL
IRSFREEMNA LLKQWH
//
