ID A4SP58_AERS4 Unreviewed; 464 AA.
AC A4SP58;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:ABO90680.1};
GN OrderedLocusNames=ASA_2659 {ECO:0000313|EMBL:ABO90680.1};
OS Aeromonas salmonicida (strain A449).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=382245 {ECO:0000313|EMBL:ABO90680.1, ECO:0000313|Proteomes:UP000000225};
RN [1] {ECO:0000313|Proteomes:UP000000225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A449 {ECO:0000313|Proteomes:UP000000225};
RX PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA Brown L.L.;
RT "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT the evolution of a fish pathogen.";
RL BMC Genomics 9:427-427(2008).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP000644; ABO90680.1; -; Genomic_DNA.
DR RefSeq; WP_005310309.1; NC_009348.1.
DR AlphaFoldDB; A4SP58; -.
DR STRING; 29491.GCA_000820065_00220; -.
DR KEGG; asa:ASA_2659; -.
DR PATRIC; fig|382245.13.peg.2629; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_5_0_6; -.
DR Proteomes; UP000000225; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ABO90680.1};
KW Cilium {ECO:0000313|EMBL:ABO90680.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:ABO90680.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 11..110
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 216..451
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 464 AA; 49107 MW; B87D70146A4D0E1C CRC64;
MTTITSAGAG SGLDLESVIA ASVDAKKAQL LQPITTKKTN AQITLSGVGQ LKSAIASFVT
TLKAMSKDDA FNKRAINITQ DKDNPVLKVE SKTGASNGQY DISVKKLATT SKFEGVFDKS
TDPMVTQDGK LTFKAGDKTF DVDVKAGDTL QSIRKRINND GDNFGLSVNI MNTSDGKSKL
VIDSGVSGTG KDLQITGNTT ELTDNFISKL TKKQDAQDAE ISVDGSTLTS VTNTFDGTIL
GLKVTVLRAS DSTTDGTTTT YKSSKVDVTT DKAGIKDMVK SFIDGYNALV KKSGDLGKRS
SIVAGVSQND GGALAGDATT RAVINMMNGA ITEPSKNSST FSSIFQLGVK MDNKGVLSLD
SEKFDEAVDK NFDQVVALFG GKDGVAGKMA GQLESYSKTG GLLAKREDSL NSDLRDVNRK
QSDVSAQLTK YEETLRARYG SLDSMLAKMN KSASYLNLLN TKSS
//
