ID   A4T4F6_MYCGI            Unreviewed;       950 AA.
AC   A4T4F6;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=FAD linked oxidase domain protein {ECO:0000313|EMBL:ABP43441.1};
GN   OrderedLocusNames=Mflv_0957 {ECO:0000313|EMBL:ABP43441.1};
OS   Mycolicibacterium gilvum (strain PYR-GCK) (Mycobacterium gilvum (strain
OS   PYR-GCK)).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350054 {ECO:0000313|EMBL:ABP43441.1};
RN   [1] {ECO:0000313|EMBL:ABP43441.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP43441.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C., Richardson P.;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABP43441.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PYR-GCK {ECO:0000313|EMBL:ABP43441.1};
RX   PubMed=23469141;
RA   Badejo A.C., Badejo A.O., Shin K.H., Chai Y.G.;
RT   "A Gene Expression Study of the Activities of Aromatic Ring-Cleavage
RT   Dioxygenases in Mycobacterium gilvum PYR-GCK to Changes in Salinity and pH
RT   during Pyrene Degradation.";
RL   PLoS ONE 8:E58066-E58066(2013).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; CP000656; ABP43441.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4T4F6; -.
DR   STRING; 350054.Mflv_0957; -.
DR   KEGG; mgi:Mflv_0957; -.
DR   eggNOG; COG0247; Bacteria.
DR   eggNOG; COG0277; Bacteria.
DR   HOGENOM; CLU_010756_0_0_11; -.
DR   OrthoDB; 9770306at2; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
FT   DOMAIN          43..266
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   DOMAIN          602..633
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   950 AA;  99792 MW;  D06306FADB06E6D2 CRC64;
     MLRPCSVLPV PESLADTLRR AGIADVRVDA TSRAAYSSDA SLYRVTPTAV VFPTGHDDVH
     AVLDVCRSEG VPVTARGGGT SIAGNAIGAG VVLDFSRYMN RVLSIDPDAQ IAVVQPGVVQ
     AVLQSEAAPF GLRFGPDPSS LSRCTIGGMI GNNACGSRAL GYGRTSDNVA ALRVLTARGE
     ELRLTSSGPG TRSPAPSSPI PRALSELTRA GMGTIRTEFG RFGRQVSGYS LEHLLPENGF
     DVSRLLVGSE GTLAVCTEAT VALVREPAHR VLVVLGFPDI ASAGDATPAI LRHRPTACEG
     IDSRIVDVVR ERKGDNAVPP LPRGAAWVFV EVVGDTAEEA LARAAEVGSG CGAVDSLVVG
     EGGRAAALWR IRADGAGLAA RSPRGRPAHA GWEDAAVPPD RLGDYLRDFD ALMAEFGATG
     MPYGHFGDGC MHVRIDLPLD RPGGVAVFRE FMVAAAHLVA GYGGSLSGEH GDGRARSELL
     PVMYSAEALA LLAAVKHAFD PDNLLNPGVV VDPRALDADL RVPAAAPIRH DLALAYRHDG
     GDFTQAVHRC TGVGKCRADN TDTGGVMCPS YLATREEKDS TRGRARVLQE MINGADVRGG
     WRSPEVHEAL DLCLSCKGCA SDCPTGVDMA AYKSEVLHQS YRRRLRPASH YSLGWLPRWA
     KLGSAVPRLA NRAAHLPGLG AAALAAAGVD RRRSIPPLAS QTFRSWFASR PASPAAGDEV
     LLFVDTFTNY FTPDVGIATV RVLESAGYRP TLTGKQLCCG LTWISTGQLD TARRTLTRSL
     TAMAPAARRG VPIVGIEPSC TAVLRSDADE LVGGEIAAQV GAATRTLAEL LTARGWTPPS
     LQGRHVVAQP HCHHHSVMGW STDAALLRGA GAEVSRLGGC CGLAGNFGVE KGHYEVSVAV
     AEQQLLPAVR GAGPATAILA DGFSCRTQLD DLTDRHGIHL AQLLARNLED
//